Dosage exam 3 Flashcards
Lupron
erosion-controlled system
leuprolide acetate/PLA
advanced prostate cancer
Zoladex
erosion-controlled system
foserelin acetate/PLGA
prostate cancer, breast cancer, endometriosis
Nutropin
erosion-controlled system
human growth hormone/PLGA
growth hormone deficiency
Gliadel Wafer
erosion-controlled system
BCNU/polyanhydride
high-grade malignant flioma
Oros tablet
Osmotic system
Release due to osmotic pressure difference and
diffusion
Benzocaine
topical effects deep tissue: local anesthetics
hydroquinone
topical effects deep tissue: lighten excessively pigmented skin
5-fluorouracil
topical effects deep tissue: skin-cancer
aluminum chloride
topical action on skin glands: antiperspirant
retinoids
topical, reset processes of epidermal proliferation and differentiation
petrolatum
polyethylene dissolved in mineral oil (Plastibase)
ointment, hydrocarbon base
polydimethylsiloxane oil
ointment, silicone base
ointment containing W/O emulsifiers, aqueous solution of a drug
ointment, absorption bases
polyethylene glycol ointment
ointment, water soluble bases
tragacanth
polymer for gel
pectin
polymer for gel
carrageenan
polymer for gel
methylcellulose
polymer for gel
carboxymethylcellulose
polymer for gel
carbopol
polymer for gel
ascorbate
enhancer for topical transdermal, reducing agent, disrupt disulfide bonds of proteins in keratinized cells
dithiothreitol
enhancer for topical transdermal, reducing agent, disrupt disulfide bonds of proteins in keratinized cells
azone (laurocapram)
enhancer for topical transdermal, nonpolar, oily liquid, fluidize intracellular lipid lamella region of stratum corneum
(makes paracellular space bigger)
diemthyl sulfoxide (DMSO)
dipolar solvent, enter aqueous region of stratum corneum, interact with lipid polar heads to expand hydrophilic region between polar heads
polyvinylpyrrolidone (PVP)
polymer used to make microneedles, water soluble
