Dopaminergic Pathways Flashcards

1
Q

Dopaminergic Pathways

A

Mesocortical
Mesolimbic
Nigrostriatal
Tuberoinfundibular

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2
Q

Mesocortical course

A

midbrain ventral tegmental area–>prefrontal

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3
Q

Mesolimbic course

A

Midbrain ventral tegmental area–>Nucleus accumbens

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4
Q

Nigrostriatal course

A

midbrain Substantia nigra releases D1 and D2 in the basal ganglia

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5
Q

Tuberoinfundibular

A

Hypothalamus–>Anterior Pituitary–>Inhibits prolactin

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6
Q

Dopaminergic pathway associated with negative symptoms of schizophrenia from decreased activity

A

Mesocortical (anergia, apathy, lack of spontaniety)

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7
Q

Dopaminergic pathway associated with positive symptoms of schizophrenia from increased activity

A

Mesolimbic (hallucinations, delusions)

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8
Q

Dopaminergic pathway associated with extrapyramidal symptoms/Parkinsons

A

Nigrostriatal pathway (dystonia, akathisia, parkinsonism, tardive dyskinesia)

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9
Q

Dopaminergic pathway associated with hyperprolactinemia

A

tuberoinfundibular

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