Dopa Researchers Flashcards

1
Q

dopa imbalances may be caused by genes Gottesmen

A

indices of skizo in cousins grandchildren half siblings pearents siblings on identical twins and identical twins
as genetic similarity increased so did the possibility of both individuals having schizo

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2
Q

measuring metabolites

A

dopa becomes metabolised into HVA (homovallinic acid cerebrospinal fluid) to get a cereb it requites a lumbar puncture. these are very intsnse and painful procedure. neg side effects- servear headaches

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3
Q

the role of serotonin

A

newer antipsychotic drugs eg conventional antipsychotics traditionally woked by blocking D2 receptor sites . not all benefit
atypical antipsychotics g clozapine black D2 and also serotonin 5HT2A equally.

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4
Q

cause or effect- crook

A

2000
used pet scans not able to predict differences in dopa activity in brain of individuals with and without schizophrenia

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