Antipsychotic Drugs Researchers Flashcards
Effectiveness- comparing conventional and atypical antipsychotics- Ravanic
(2009)
Clozapine improved symptoms more than haloperidol and chlorpromazine (older drugs) over 5 years
Clozapine caused fewer side effects average of 0.9 side effects per patient compared to 2.7 for haloeridol and 3.2 for chlorpromazine
Effectiveness- antipsychotics can effectively treat schizophrenia- Cole
1964
75% ppl taking conventional antipsychotics improved compared to only 25% ho were gieven a placebo
Non of patients taking the drug go worse
48% of placebo group did
Effectiveness- hard to measure the effectiveness- Rattenacher
(2004)
54.2% of ppl with schizophrenia fully took meds
8.3% took it sometimes
37.5% didn’t take it
Ethics- side effects- ……… (researchers have to consider?)
Tardive dyskinesia (involuntary movements)
Parkinsonism (tremors and instability)
Seizures
Agranulocytosis (life threatening drop in white blood cells)
During a cute episodes patients are given drugs without consent
Ethics - chemical straitjackets- Antipsychotic movement and snasz
Antipsychotics act like “chemical straitjackets” making people quiet and easy to manage
(1960)
Society uses mental illness as a way to control people who don’t fit in instead of helping
Social- asylums or care in the community- Laurie
(2011)
Drugs changed schizo from an untreatable condition needing lifelong care to one where patients can live independently and recover
Benefits patients by reducing stigma and hospital costa
Social- risk to violence- tihonen and NCIH
(2006)
37 fold increase in those who stopped meds irrational movements may injury self or others
(2015)
Linked 29% of 346 homoicides by people with schizophrenia to non adherence.