Antipsychotic Drugs Researchers Flashcards

1
Q

Effectiveness- comparing conventional and atypical antipsychotics- Ravanic

A

(2009)
Clozapine improved symptoms more than haloperidol and chlorpromazine (older drugs) over 5 years
Clozapine caused fewer side effects average of 0.9 side effects per patient compared to 2.7 for haloeridol and 3.2 for chlorpromazine

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2
Q

Effectiveness- antipsychotics can effectively treat schizophrenia- Cole

A

1964
75% ppl taking conventional antipsychotics improved compared to only 25% ho were gieven a placebo
Non of patients taking the drug go worse
48% of placebo group did

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3
Q

Effectiveness- hard to measure the effectiveness- Rattenacher

A

(2004)
54.2% of ppl with schizophrenia fully took meds
8.3% took it sometimes
37.5% didn’t take it

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4
Q

Ethics- side effects- ……… (researchers have to consider?)

A

Tardive dyskinesia (involuntary movements)
Parkinsonism (tremors and instability)
Seizures
Agranulocytosis (life threatening drop in white blood cells)

During a cute episodes patients are given drugs without consent

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5
Q

Ethics - chemical straitjackets- Antipsychotic movement and snasz

A

Antipsychotics act like “chemical straitjackets” making people quiet and easy to manage

(1960)
Society uses mental illness as a way to control people who don’t fit in instead of helping

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6
Q

Social- asylums or care in the community- Laurie

A

(2011)
Drugs changed schizo from an untreatable condition needing lifelong care to one where patients can live independently and recover
Benefits patients by reducing stigma and hospital costa

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7
Q

Social- risk to violence- tihonen and NCIH

A

(2006)
37 fold increase in those who stopped meds irrational movements may injury self or others
(2015)
Linked 29% of 346 homoicides by people with schizophrenia to non adherence.

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