DOACs Flashcards

1
Q

Apixiban + rivaroxaban Antidote

A

Andenext alfa

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2
Q

Dabigatran antidote

A

Idarucizumab

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3
Q

Edoxaban antidote

A

There is not antidote

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4
Q

Dose adjustments in Renal

A

Crcl <15ml/min - Avoid rivaroxaban, apixaban, edoxaban

Crcl <30ml/min - Avoid dabigatran

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5
Q

Reducing dose Apixaban criteria

A

Any 2 of:

> 80 years
<61kg
Creatine clearance of >133 micro mol/L

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6
Q

What doses of rivaoxaban should be given with food

A

15mg and 20mg - lack of efficacy at these doses without food
Can be crushed and mix with water or apple puree

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7
Q

Can DOACs be used in antiphospholipid syndrome

A

No switch to warfarin

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8
Q

Dabigatran SE

A

Abnormal Hepatic function

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9
Q

Apixiban and Edoxaban SE

A

Bleeding
Anaemia
Nausea
Skin reactions

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