DNA Replication Flashcards
1
Q
DNA replication
A
semiconservative
2
Q
replication forks
A
bidirectional
both strands replicate
3
Q
bacterial replication
A
binary fission
4
Q
replicons
A
multiple replication units
5
Q
DNA polymerase
A
- DNA as template
- synthesis 5’–>3’
6
Q
Okazaki fragments
A
formed from lagging strand and uses DNA ligase to join
7
Q
primase
A
synthesize short RNA primers
8
Q
DNA polymerase (III)
A
adds nucleotides to 3’ end of primer
9
Q
DNA polymerase (I)
A
replaces RNA with DNA
10
Q
DNA alteration
A
mutation
11
Q
loss of purine base
A
depurination
12
Q
removal of a base’s amino group
A
deamination
13
Q
recruited to DNA by proteins to recognize damage
A
endonucleases
14
Q
single strand: pathway removes the incorrect nucleotides and filled properly with what?
A
cut-and-path
15
Q
double strand:
non homologous end-joining
A
proteins bind to the broken end and join them together
