DNA Replication

Question 1

Steps of DNA Replication

Answer 1

1. Identify Origins of replication
2. unwind
3. prime and elongate
4. ligate
5. assemble to chromatin

Question 2

ORC

Answer 2

Origin of Replication Complex. Binds to DNA in late M1 early G1

Question 3

Cdt1/Cdt6 and MCM

Answer 3

licensing factors. MCM is helicase and unwinds DNA

Question 4

Primase

Answer 4

RNA/DNA alpha. primes DNA

Question 5

DNA Polymerase

Answer 5

DNA pol DELTA clamps on

Question 6

Topoisomerase

Answer 6

prevents overwinding

Question 7

How does DNA repair phosphodiester nick in Okazaki Fragments

Answer 7

dna ligase + ATP

Question 8

Telomerase

Answer 8

Reverse Transcriptase