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FOM Summative > Cell Injury and Adaptation III > Flashcards

Cell Injury and Adaptation III Flashcards

1
Q

How do Hydroxyl radicals cause damage

A
  1. lipid peroxidation (damaging cell membranes)
  2. Damage to proteins (enzymes/structure)
  3. Single and Doublestranded breaks in DNA
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2
Q

How can a large increase in Calcium levels contribute to damage?

A

Increases enzyme activity/ROS effects leading to membrane damage

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3
Q

HIF-1

A

promotes blood vessel formation, and this causes diabetic retinopathy

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4
Q

FAS

A

Binds to activator on T cells to start caspase

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5
Q

Dystrophic Calcification

A

can occur at any calcium level

occurs in previously injured tissue (think heart damage)

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6
Q

Metastatic Calcificiation

A

High calcium levels
often related to bone calcification
occurs

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FOM Summative (19 decks)

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