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biology topic 1 > DNA replication > Flashcards

DNA replication Flashcards

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AP® Biology flashcards Biology 101 flashcards
1
Q

who proposed the semi conservative replication of DNA model

A

watson and crick

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2
Q

what is the semi conservative replication of DNA

A

DNA helicase hydrolyses H bonds
unwinds helix
two strands act as a template
free floating DNA nucleotides attracted to exposed bases via complementary base pairing
DNA polymerase joins adjacent nucleotidides by consensation
forming phosphodiester bonds

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3
Q

why is it called semi conservative replication

A

each new helix contains one origninal template strand and one new strand
ensures genetic continuity

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4
Q

how does DNA polymerase move

A

oppisite directions along strands
DNA has anti parallel stands
DNA polymerase is an enzyme with a specific shaped active site
can only bind and add nucleotides to phosphate (3) end

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5
Q

what evidence supports semi conservative replication of DNA model

A

Meselson and Stahl
nitrogen isotopes

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biology topic 1 (10 decks)

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