DNA Replication Flashcards

You may prefer our related Brainscape-certified flashcards:
0
Q

Guanine base pairing

A

Only with cytosine

3 hydrogen bonds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
1
Q

Adenine base pairing

A

Only with Thymine

2 hydrogen bonds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Conservative model

A

Parent strand reforms after replication

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Dispersive model

A

New strand contains old and new fragments

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Semi-conservative model

A

Each newly synthesized helix contains one new and one old strand
Correct model

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Replication bubble

A

Proteins attach to DNA and separate strands

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Nucleoside triphosphate

A

Energy for DNA polymerase
Sugar and nitrogenous base plus 3 phosphate groups
2 phosphates get clipped off- undergo hydrolysis to create energy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

DNA polymerase III

A

Adds nucleotides to free 3’ end of DNA strand

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Okazaki fragments

A

Sections of newly synthesized DNA

Formed on lagging strand

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

DNA ligase

A

Forms bonds between Okazaki fragments, joining them together

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Primer

A

Short strand of RNA that DNA pol III adds nucleotides to

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Primase

A

Joins RNA nucleotides to make primer that is complementary to DNA strand

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

DNA polymerase I

A

Replaces RNA primer with primers of DNA nucleotides

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Helicase

A

Enzymes that untwists DNA helix @ replication fork

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Topoisomerase

A

Relieves strain caused by helicase as it unwinds DNA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Single-strand binding protein

A

Binds to unpaired DNA template strands that helicase has unwound, stabilizing them

16
Q

Nuclease

A

Excises incorrect nucleotides

17
Q

Telomeres

A

Short repetitions of DNA sequence
Complete 5’ end of DNA
Short in old or cultured cells
Longer in germ cells that give rise to gametes

18
Q

Telomerase

A

Catalyzes lengthening of telomeres
Active in germ cells but not in somatic cells
Activated by some types of cancer cells