DNA BLAST Flashcards
Chemical composition of the nucleus
Nucleon was not solely a protein due to its high concentration of phosphorus
Friedrich Miescher
Independently published papers on chromosome theory of inheritance
Genes are found at specific locations on chromosomes
NO DIRECT EVIDENCE
Walter Sutton and Theadore Boveri
Fruit flies provided direct evidence on chromosome theory of inheritance
Thomas Hunt Morgan
Heat-killed bacteria can transform a non-virulent strain — first evidence that genetic material is heat-stable chemical
Fredrick Griffith
Identify Griffiths’s transforming agent as DNA
DNA is capable of transforming the non-virulent strain of bacteria
Oswald Avery, Maclyn McCarty, Colon MacLeoed
DNA composition is species-specific
A=T
G=C
Erwin Chargaff
Bacteriophages grown in radioactive medium- DNA enters cells as the transforming agent
Alfred Hershey and Martha Chase
Spacial relationships of helical backbone
2 forms of DNA
Crystallography showed overall structure of DNA
Rosalind Franklin working in Maurice Wilkins’ lab
Compile info known about DNA and publish the DOUBLE HELIX with outer sugar phosphate-backbone and paired based facing forward
James Watson and Francis Crick
Transcription
RNA Synthesis
DNA -> RNA
Translation
Protein Synthesis
RNA -> Protein
Replication / DNA Synthesis is called
Semiconservative replication
Seem
Semiconservative replication
Replication where
2 strands of DNA that are genetically identical to the original strand
Transcription = RNA synthesis
To create proteins, we first create
Messenger RNA / mRNA
In RNA synthesis, Deoxyribose and Thymine are replaced by
Ribose and Uracil
In translation / Protein synthesis,
The mRNA is converted into proteins by the
Ribosome (site of protein synthesis)
3 letter codes
Codons
MRNA is translated into __
amino acids / EACH CODON represents on animo acid
GUA, UGC <- codons
Val, Cys - the names translated are__
Amino acids
Amino acids together form a
Val-Cys-Lys-Ser-Leu
Polypeptide chain
Which FOLD into proteins
Genetic code
Each codon will code for an amino acid
Anime acids are __ of proteins
Monomers
In replication you make a copy of the DNA
In Transcription you make mRNA to make a complementary copy of the DNA strand