DNA Flashcards
Genotype
genetic message
Central Dogma
DNA to RNA to Protein, this path is central Dogma
transcription takes place in
DNA to RNA, in nucleus
PHENOTYPE
physical expression of genetic expression
Translation takes place in
RNA to proteins, outside of nucleus in ribosomes
HOW is the genotype translated into phenotypes?
by the formation of proteins
who first transferred hereditary material from dead cells to live cells
Griffith, R cells-not deadly; S cells: Deadly
Hershey and Chase experiment
proved DNA is the hereditary material, not protein; protein parts of the virus is labeled with 35S, stayed outside the bacteria
DNA of viruses, labeled with 32P, entered the bacteria
Watson and Crick
built an alpha double helix model of DNA that says a DNA molecule consists of two nucleotides chains (strands) running in opposite directions and coiled into double helix.
Base pairs form on the inside of the helix, held together by hydrogen bonds.
Avery and McCarthy
find ‘DNA’ as the hereditary material from Griffith experiment
Chargaff’s first rule
A=T, G =C : the amount of Adenine and thymine in DNA are the same, Guanine and Cytosine are the same
each chromosome consists of …… strand of DNA
one strand of DNA
sister chromatids
when cell prepares to divide, it duplicates all of its chromosomes and each duplicated chromosome has two DNA strands like X, and each bunched filament is called a sister chromatid. joined together at centromere.
Chargaff’s second rule
the portion of Adenine and Guanine differs between different species of organisms.