DNA Flashcards
1
Q
Maurice Wilson and Rosalind Franklin
A
conducted xray crystallography studies of DNA and proteins, couldn’t figure out whether DNA or proteins carried genetic info
2
Q
James Watson and Francis Crick
A
won Nobel Prize for structure of DNA
3
Q
Structure of DNA
A
- double helix
- 4 nucleotides
- deoxyribonucleic acid
- eukaryotes have linear DNA, prokaryotes have circular DNA
4
Q
width of DNA double helix
A
2.0 nm
5
Q
distance between bases
A
0.34 nm
6
Q
length of 1 complete turn of the helix
A
3-4 nm
7
Q
DNA nucleotide consist of
A
phosphate group, deoxyribose sugar, nitrogenous base (1 of 4)
8
Q
Thymine (T)
A
- single ring (pyrimidine)
- bonds with adenine (A)
- 2 H-bonds
- Uracil replaces thymine in RNA
9
Q
Adenine (A)
A
- double ring (purine)
- bonds with thymine (T) in DNA
- bonds with uracil (U) in RNA
- 2 H-bonds
10
Q
Cytosine (C)
A
- single ring (pyrimidine)
- bonds with guanine (G)
- 3 H-bonds
11
Q
Guanine (G)
A
- double ring (purine)
- bonds with cytosine (C)
- 3 H-bonds
12
Q
5’ end
A
phosphate group
13
Q
3’ end
A
hydroxyl group
14
Q
the two strands of a DNA molecule are…
A
antiparallel
