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Naplex > DM AE/CI > Flashcards

DM AE/CI Flashcards

1
Q

↑/Replaces Insulin Secretion

A

Insulin
SU
Meglitinides

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2
Q

↓Hepatic Glucose Output

A

Metformin

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3
Q

↓Glucagon → ↓glucose production

A

GLP1 agonists
DPP4i
Pramlintide

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4
Q

Slows Gastric Emptying

A

GLP1 agonists

Pramlintide

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5
Q

↑Glucose Excretion

A

SGLT2i

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6
Q

↑ Insulin Sensitivity

A

TZD

Metformin

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7
Q

Biggest ↓A1c

A 
Insulin
metformin
SU
TZD
GLP1
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8
Q

Cardiac Benefits

A 
empagliflozin
canagliflozin
dapagliflozin
liraglutide
semaglutide
exenatide
dulaglutide
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9
Q

Weight loss

A

SGLT2i
GLP1
pramlintide

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10
Q

Cheapest

A

Metformin
SU
TZD

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11
Q

Greatest Hypoglycemia

A

Insulin
SU
meglitinides
pramlintide (w/insulin)

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12
Q

Weight gain

A

Insulin
SU
meglitinide
TZD

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13
Q

Injectable Drugs

A

Insulin
GLP1
pramlintide

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14
Q

CI: eGFR or CrCl < 30

A

Metformin
SGLT2i
exenatide
glyburide

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15
Q

CI: HF

A

TZD
alogliptin
saxagliptin

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16
Q

CI: Peripheral neuropathy, PAD, diabetic foot ulcers

A

canagliflozin

17
Q

CI: Gastroparesis / GI disorder

A

GLP1

pramlintide

18
Q

CI: Sulfa allergy

19
Q

Risk of Lactic Acidosis

20
Q

Risk of Hepatotoxicity

A

TZD

alogliptin

21
Q

Risk of HoTN, UTI, Ketoacidosis

22
Q

Risk of K abnormalities

A

canagliflozin (↑K)

insulin (↓K)

23
Q

Risk of Pancreatitis

A

DPP4i

GLP1

24
Q

Risk of Hypersensitivity

A

SU
DPP4i
Insulin

25
Q

Risk of Cancer

A

Pioglitazone
Dapagliflozin
GLP1

Naplex (5 decks)

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