COPD Flashcards

1
Q

General Information

A
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2
Q

COPD Key Features

A

Age of onset > 40yo

Smoking hx > 10 years

Sputum production

Persistent symptoms

Disease progressive

Exacerbations

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3
Q

COPD Diagnosis

A

Spirometry Post-bronchodilator FEV1/FVC < 0.70

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4
Q

COPD Assessment

  1. Degree of Airflow Limitation
A
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5
Q

COPD Assessment

  1. Symptoms
A
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6
Q

COPD Assessment

Comorbidities

A

CV diseases,

Osteoporosis,

Skeletal muscle dysfunction,

DM,

Depression/Anxiety,

Lung cancer

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7
Q

COPD Assessment

  1. Risk of Exacerbations
A
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8
Q

COPD Treatment Overview

A
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9
Q

Combined Assessment of COPD

A
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10
Q
A
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11
Q

Treatment Escalation - Dyspnea

A
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12
Q

Treatment Escalation - Exacerbations

A
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13
Q

Cause of COPD Exacerbations

A
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14
Q

SAMA + SABA

A

Combivent Respimat

DuoNeb

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15
Q

Combivent Respimat

A

Ipratropium + Albuterol

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16
Q

Combivent Respimat - key features

A

MDI: 1 inhalation QID SABA + SAMA combo improves FEV1 and symptoms

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17
Q

Atrovent HFA

A

Ipratropium Bromide

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18
Q

Atrovent HFA - key features

A

MDI: 2 inhalations QID

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19
Q

SAMA agents

A

Ipratropium

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20
Q

SAMA, LAMA key features

A
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21
Q

Turdoza Pressair

A

Aclidinium
LAMA

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22
Q

Turdoza Pressair key features

A

DPI: 1 inhalation BID Indicator window: Green → Red

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23
Q

Seebri Neohaler

A

Glycopyrrolate

LAMA

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24
Q

Lonhala Magnair

A

Glycopyrrolate

LAMA

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25
Seebri Neohaler Key features
Neohaler DPI: 1 cap BID
26
Lonhala Magnair key features
Nebulizer
27
Yupelri
Revefenacin
28
Yupelri key features
Nebulizer solution
29
Respimat
Tiotropium
30
Spiriva HandiHaler
Tiotropium
31
Spiriva Handihaler key features
HandiHaler DPI: 1 cap Qday (2 puffs)
32
Respimat key features
Respimat MDI: 2 inh Qday
33
Incruse Ellipta
Umeclidinium
34
Incruse Ellipta key features
DPI: 1 inh daily
35
Serverent Diskus
Salmeterol
36
Perforomist
Formoterol
37
Brovana
Arfomoterol
38
Arcapta Neohaler
Indacaterol Neohaler DPI: 1 cap Qday
39
Striverdi Respimat
Olodaterol MDI: 2 inhalations Qday
40
LABA - Key features
41
LAMA + LABA
Duakir Pressair Bevespi Aerosphere Utibron Neohaler Stiolto Respimat Anoro Ellipta
42
Duakir Pressair
Aclidinium + Formoterol DPI: 1 inhalation BID
43
Bevespi Aerosphere
Glycopyrrolate + formoterol
44
Utibron Neohalter
Glycopyrrolate + Indacaterol Neohaler DPI: 1 cap BID
45
Stiolto Respimat
Tiotropium + olodaterol Respimat MDI: 2 inhalations Qday
46
Anoro Ellipta
Umeclidinium + Vilanterol ## Footnote **DPI: 1 inhalation daily**
47
LABA + ICS LABA + LAMA + ICS key features
Rinse mouth after use
48
Symbicort
Formoterol + budesonide
49
Advair Diskus
Salmeterol + fluticasone
50
Wixela Inhub
Salmeterol + Fluticasone
51
Breo Ellipta
Vilanterol + fluticasone
52
Trelegy Ellipta
Umeclidinium + Vilanterol + Fluticasone Rinse mouth after use
53
PDE-4 i
Roflumilast
54
Daliresp
Roflumilast
55
Roflumilast key features
MOA: PDE-4 inhibitor → ↑cAMP → ↓lung inflammation Must use with ≥ 1 long-acting bronchodilator C/I: Mod to severe liver impairment | ADR: Diarrhea, weight loss
56
Metered Dose Inhalers - HFA
57
Metered Dose Inhalers - Respimat
58
Dry Powder Inhalers - Ellipta
59
Dry Powder Inhaler - Pressair
60
Dry Powder Inhaler - Handihaler
61
Dry Powder Inhaler - Neohaler