COPD Flashcards

1
Q

General Information

A
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2
Q

COPD Key Features

A

Age of onset > 40yo

Smoking hx > 10 years

Sputum production

Persistent symptoms

Disease progressive

Exacerbations

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3
Q

COPD Diagnosis

A

Spirometry Post-bronchodilator FEV1/FVC < 0.70

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4
Q

COPD Assessment

  1. Degree of Airflow Limitation
A
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5
Q

COPD Assessment

  1. Symptoms
A
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6
Q

COPD Assessment

Comorbidities

A

CV diseases,

Osteoporosis,

Skeletal muscle dysfunction,

DM,

Depression/Anxiety,

Lung cancer

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7
Q

COPD Assessment

  1. Risk of Exacerbations
A
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8
Q

COPD Treatment Overview

A
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9
Q

Combined Assessment of COPD

A
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10
Q
A
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11
Q

Treatment Escalation - Dyspnea

A
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12
Q

Treatment Escalation - Exacerbations

A
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13
Q

Cause of COPD Exacerbations

A
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14
Q

SAMA + SABA

A

Combivent Respimat

DuoNeb

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15
Q

Combivent Respimat

A

Ipratropium + Albuterol

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16
Q

Combivent Respimat - key features

A

MDI: 1 inhalation QID SABA + SAMA combo improves FEV1 and symptoms

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17
Q

Atrovent HFA

A

Ipratropium Bromide

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18
Q

Atrovent HFA - key features

A

MDI: 2 inhalations QID

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19
Q

SAMA agents

A

Ipratropium

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20
Q

SAMA, LAMA key features

A
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21
Q

Turdoza Pressair

A

Aclidinium
LAMA

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22
Q

Turdoza Pressair key features

A

DPI: 1 inhalation BID Indicator window: Green → Red

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23
Q

Seebri Neohaler

A

Glycopyrrolate

LAMA

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24
Q

Lonhala Magnair

A

Glycopyrrolate

LAMA

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25
Q

Seebri Neohaler Key features

A

Neohaler DPI: 1 cap BID

26
Q

Lonhala Magnair key features

A

Nebulizer

27
Q

Yupelri

A

Revefenacin

28
Q

Yupelri key features

A

Nebulizer solution

29
Q

Respimat

A

Tiotropium

30
Q

Spiriva HandiHaler

A

Tiotropium

31
Q

Spiriva Handihaler key features

A

HandiHaler DPI: 1 cap Qday (2 puffs)

32
Q

Respimat key features

A

Respimat MDI: 2 inh Qday

33
Q

Incruse Ellipta

A

Umeclidinium

34
Q

Incruse Ellipta key features

A

DPI: 1 inh daily

35
Q

Serverent Diskus

A

Salmeterol

36
Q

Perforomist

A

Formoterol

37
Q

Brovana

A

Arfomoterol

38
Q

Arcapta Neohaler

A

Indacaterol

Neohaler DPI: 1 cap Qday

39
Q

Striverdi Respimat

A

Olodaterol

MDI: 2 inhalations Qday

40
Q

LABA - Key features

A
41
Q

LAMA + LABA

A

Duakir Pressair

Bevespi Aerosphere

Utibron Neohaler

Stiolto Respimat

Anoro Ellipta

42
Q

Duakir Pressair

A

Aclidinium + Formoterol

DPI: 1 inhalation BID

43
Q

Bevespi Aerosphere

A

Glycopyrrolate + formoterol

44
Q

Utibron Neohalter

A

Glycopyrrolate + Indacaterol

Neohaler DPI: 1 cap BID

45
Q

Stiolto Respimat

A

Tiotropium + olodaterol

Respimat MDI: 2 inhalations Qday

46
Q

Anoro Ellipta

A

Umeclidinium + Vilanterol

DPI: 1 inhalation daily

47
Q

LABA + ICS

LABA + LAMA + ICS

key features

A

Rinse mouth after use

48
Q

Symbicort

A

Formoterol + budesonide

49
Q

Advair Diskus

A

Salmeterol + fluticasone

50
Q

Wixela Inhub

A

Salmeterol + Fluticasone

51
Q

Breo Ellipta

A

Vilanterol + fluticasone

52
Q

Trelegy Ellipta

A

Umeclidinium + Vilanterol + Fluticasone

Rinse mouth after use

53
Q

PDE-4 i

A

Roflumilast

54
Q

Daliresp

A

Roflumilast

55
Q

Roflumilast key features

A

MOA: PDE-4 inhibitor → ↑cAMP → ↓lung inflammation

Must use with ≥ 1 long-acting bronchodilator

C/I: Mod to severe liver impairment | ADR: Diarrhea, weight loss

56
Q

Metered Dose Inhalers - HFA

A
57
Q

Metered Dose Inhalers - Respimat

A
58
Q

Dry Powder Inhalers - Ellipta

A
59
Q

Dry Powder Inhaler - Pressair

A
60
Q

Dry Powder Inhaler - Handihaler

A
61
Q

Dry Powder Inhaler - Neohaler

A