DLA3- Anti-Anxiolytic

Question 1

define anxiety disorder

Answer 1

episodes of anxiety that impair a person’s functioning

Question 2

Anxiety Disorder:

• (1) long-term drug of choice
• (2) short-term drug of choice

Answer 2

1- SSRIs (GAD, SAD, PTSD, PD, OCD) –> 2nd choice antidepressants –> bupropion is less effective then others

2- benzodiazepines (limited in PTSD, OCD)

Question 3

describe the drugs of choice for GAD

Answer 3

1st: antidepressants long-term, benzodiazepines short-term
2nd: buspirone (NDRI)
3rd: hydroxyzine (H1), pregabalin (GABA)

Question 4

describe drugs of choice for PD

Answer 4

(panic disorder)

1st: SSRI > TCA > MAOI long-term // benzodiazepines short-term (alprazolam)

Question 5

______ is drug of choice for SAD

Answer 5

(social anxiety disorder)

SSRIs

Question 6

describe drugs of choice for OCD

Answer 6

SSRIs (more AEs)

Clomipramine; TCA

Question 7

describe drugs of choice for PTSD

Answer 7

1st: SSRIs
2nd: SNRI (venlafaxine), TCA, MAOI

Question 8

(1) is the drug of choice for performance anxiety with (2) as the main AE

Answer 8

1- β-blokers – propanolol, nadolol

2- hypotension