Diverticular disease Flashcards
What is diverticular disease?
Herniation of colonic mucosa through the muscular wall of the colon
Pathophysiology of diverticular disease
- Bowel weakens with age
- Movement of stool within lumen causes an ↑ in luminal pressure
- Results in outpouchings of mucosa through weaker areas of the bowel wall
- Bacteria overgrow within outpouchings, leading to diverticulitis
Which area of the intestine does diverticular disease affect?
Sigmoid - between the taenia coli
The rectum (lacks taenia) is often spared
How does diverticular disease present?
- Constipation
- Left lower quadrant pain (colicky, relieved by defecation)
- Some patients experience rectal bleeding
Imaging investigations for diverticular disease
colonoscopy, CT cologram or barium enema
List 4 risk factors for diverticular disease
- Increased age
- Low fibre diets
- obesity
- use of NSAIDs
How is diverticular disease diagnosed?
Colonoscopy or CT scans (often incidentally)
Examination findings of diverticular disease?
- May be normal
- May be tenderness in the left lower quadrant
- May be tenderness on digital rectal examination
Treatment if diverticular disease?
- High fibre diet and weight loss
- Bulk-forming laxatives (eg. ispaghula husk)
- Weight loss
If severe, surgery to remove affected area may be required
List 2 common complications of diverticular disease?
- Strictures - due to repeated episodes of inflammation
- Fistulas (Colovesical and Colovaginal)
What is Diverticulitis?
Inflammation in the diverticula
How does diverticulitis present?
- Pain and tenderness in left iliac fossa
- Fever
- Diarrhoea
- Nausea and vomiting
- Rectal bleeding
- Palpable abdominal mass (if abscess)
- Raised inflammatory markers (CRP) and WBCs
List 4 signs of diverticulitis
- Low grade pyrexia
- Tachycardia
- Tender LIF
- Guarding, rigidity and rebound tenderness (complicated)
First line imaging for diverticulitis?
List 3 changes which may be seen
CT abdomen-pelvis:
- Thickening of colonic wall
- Pericolonic fat stranding
- Abscesses
- localised air bubbles or free air
Are Colonoscopy’s used in patients presenting with suspected diverticular disease?
NO, due to increased risk of perforation