Diuretics simple

Question 1

Furosemide mechanism:

Answer 1

Loop diuretic. Blocks NaK2Cl pump

Question 2

Bumetanide mechanism:

Answer 2

Loop diuretic. Blocks NaK2Cl pump

Question 3

Chlorthalidone mechanism:

Answer 3

Thiazide. Blocks NaCl pump in distal tubule

Question 4

Hydrochlorothiazide mechanism:

Answer 4

Blocks Na/Cl pump in distal tubule. Note, lose K+ too b/c Na/K antiport further down pathway

Question 5

Metalazone mechanism:

Answer 5

Thiazide. Blocks Na/Cl pump in distal tubule

Question 6

Sprinolactone mechanism:

Answer 6

Inhibits aldosterone, so potassium saring by stopping the sodium/potassium anti port that it would normally cause to happen

Question 7

Amiloride mechanism:

Answer 7

Blocks Enac, so Na/K antiport doesnt happen and potassium is spared

Question 8

Triamteren mechanism:

Answer 8

Blocks Enac, so Na/K antiport doesnt happen and potassium is spared

Question 9

Desmopressin mechanism:

Answer 9

acts like vesopressin

Question 10

Demeocycline mechanism:

Answer 10

ADH antagonist, so water let out

Question 11

Mannitol mechanism:

Answer 11

duh

Question 12

Acetazolamide mechanism:

Answer 12

No bicarb resorption in proximal tubule. Urine is alkaline