DIURETICS

Question 1

Example of Osmotic diuretic

Answer 1

Mannitol

Question 2

Site of action of osmotic diuretics

Answer 2

Proximal tubule

Question 3

Mechanism of osmotic diuretic

Answer 3

Osmotically draws water out of the ICF

Question 4

Use of osmotic diuretic

Answer 4

Used in acute settings as it is fast acting

Question 5

Site of action of Carbonic anhydrase inhibitors

Answer 5

Proximal tubule

Question 6

Mechanism of carbonic anhydrase inhibitor

Answer 6

Inhibits CA

Question 7

Use of carbonic anhydrase

Answer 7

Glaucoma

Question 8

Example of loop diuretic

Answer 8

Furosemide

Question 9

Site of action of loop diuretics

Answer 9

Thick ascending limb

Question 10

Mechanism of loop diuretics

Answer 10

blocks Na/K/2Cl symporter

Question 11

Use of loop diuretics

Answer 11

most effective

Question 12

Example of thiazide diuretic

Answer 12

hydrochlorothiazide

Question 13

Site of action of thiazide diuretics

Answer 13

Distal tubule

Question 14

Mechanism of thiazide diuretics

Answer 14

inhibits Na/cl symporter

Question 15

Use of thiazide diuretics

Answer 15

K sparring

Question 16

Example of ENaC inhibitor

Answer 16

Amiloride

Question 17

Site of action of ENaC inhib.

Answer 17

collecting duct

Question 18

Mechanism of ENaC inhib.

Answer 18

inhibits ENaC channel

Question 19

Use of ENaC inhib.

Answer 19

K sparring

Question 20

Example of mineralocortical receptor antagonist

Answer 20

spirinolactone

Question 21

Site of action of mineralocortical receptor antagonist

Answer 21

Collecting duct

Question 22

Mechanism of mineralocortical receptor antagonist

Answer 22

aldosterone antagonist, decreases the amount of ENaC and Na/KATPase

Question 23

Use of mineralocortical receptor antagonist

Answer 23

K sparring

Question 24

Example of a methylxanthine

Answer 24

Caffeine

Question 25

mechanism of methylxanthine

Answer 25

increase GFR via pre-renal mechanism