Diuretics Flashcards

1
Q

Thiazide diuretics

A

Chlorothiazide
Hydrochlorothiazide
Chlorthalidone
Indapamide
Metolazone

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2
Q

Diuretic type that inhibits Na/Cl cotransport in the distal convoluted tubule

A

Thiazide diuretics

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3
Q

Diuretic type that increases excretion of Na, K, Cl, Mg, and HCO3. Decreases excretion of Ca and uric acid.

A

Thiazide diuretics

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4
Q

Diuretic type associated with an increase in plasma cholesterol and triglycerides, and the exception.

A

Thiazide diuretics, except indapamide

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5
Q

Loop diuretics

A

Furosemide
Bumetanide
Torsemide
Ethacrynic acid

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6
Q

Diuretic type that inhibits the Na/K/2Cl cotransport system. They increase excretion of Na, K, Mg, Cl, HCO3, and Ca.

A

Loop diuretics

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7
Q

Diuretic type with a possible side effect of ototoxicity and should not be taken with aminoglycosides

A

Loop diuretics

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8
Q

Osmotic diuretics

A

Mannitol
Glycerol

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9
Q

Diuretic type that increases osmotic pressure in proximal tubule to inhibit reabsorption of water and electrolytes

A

Osmotic diuretics

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10
Q

Indications for use of osmotic diuretics

A

Cerebral edema - intracranial pressure
Acute glaucoma - intraocular pressure
Acute renal failure

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11
Q

Diuretic type with the adverse effect of excessive plasma volume expansion which can lead to heart failure

A

Osmotic diuretics

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12
Q

Carbonic anhydrase inhibitor diuretics

A

Acetazolamide
Dorzolamide

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13
Q

Diuretic type that increases excretion of Na, K, and HCO3. Has side effects of drowsiness and paresthesia.

A

Carbonic anhydrase inhibitors

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14
Q

Indications for use of carbonic anhydrase inhibitors

A

Altitude sickness
Glaucoma
Overdose of acidic drugs –> alkalinizes urine

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15
Q

K-sparing diuretics

A

Spironolactone
Eplerenone
Amiloride
Triamterene

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16
Q

K sparing diuretic associated with a side effect of nephrolithiasis

A

Triamterene

17
Q

Diuretic type that blocks Na reabsorption in the collecting duct. Associated with adverse effect of hyperkalemia

A

K sparing diuretics

18
Q

Treatment of hyperkalemia

A

Patiromer

19
Q

Diuretic used for nephrogenic diabetes insipidus caused by lithium

A

Amiloride

20
Q

Antidiuretic hormone and vasopressin antognists

A

Conivaptan
Tolvaptan

21
Q

V1A and V2 receptor blocker used in euvolemic and hypervolemic hyponatremia

A

Conivaptan

22
Q

Selective V2 receptor blocker used in euvolemic and hypervolemic hyponatremia

A

Tolvaptan

23
Q

Adverse effects of conivaptan and tolvaptan

A

Infusion site reaction
Hypokalemia