Diuretics Flashcards
Thiazide diuretics
Chlorothiazide
Hydrochlorothiazide
Chlorthalidone
Indapamide
Metolazone
Diuretic type that inhibits Na/Cl cotransport in the distal convoluted tubule
Thiazide diuretics
Diuretic type that increases excretion of Na, K, Cl, Mg, and HCO3. Decreases excretion of Ca and uric acid.
Thiazide diuretics
Diuretic type associated with an increase in plasma cholesterol and triglycerides, and the exception.
Thiazide diuretics, except indapamide
Loop diuretics
Furosemide
Bumetanide
Torsemide
Ethacrynic acid
Diuretic type that inhibits the Na/K/2Cl cotransport system. They increase excretion of Na, K, Mg, Cl, HCO3, and Ca.
Loop diuretics
Diuretic type with a possible side effect of ototoxicity and should not be taken with aminoglycosides
Loop diuretics
Osmotic diuretics
Mannitol
Glycerol
Diuretic type that increases osmotic pressure in proximal tubule to inhibit reabsorption of water and electrolytes
Osmotic diuretics
Indications for use of osmotic diuretics
Cerebral edema - intracranial pressure
Acute glaucoma - intraocular pressure
Acute renal failure
Diuretic type with the adverse effect of excessive plasma volume expansion which can lead to heart failure
Osmotic diuretics
Carbonic anhydrase inhibitor diuretics
Acetazolamide
Dorzolamide
Diuretic type that increases excretion of Na, K, and HCO3. Has side effects of drowsiness and paresthesia.
Carbonic anhydrase inhibitors
Indications for use of carbonic anhydrase inhibitors
Altitude sickness
Glaucoma
Overdose of acidic drugs –> alkalinizes urine
K-sparing diuretics
Spironolactone
Eplerenone
Amiloride
Triamterene