Diuretics Flashcards

1
Q

General diuretic assessment?

A

Daily weight

I&O

Edema

Skin turgor

Diaphoretic

Mucous membranes

Electrolyte swings

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2
Q

Fluid overload signs?

A

Altered mental status

Crackles

Jugular venous pressure goes up

Increased body weight

Increased BP

pitting edema

Altered capillary refill

Anasarka

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3
Q

Diuretic vital assessment?

A

Assess for fluid overload

Lung sounds for crackles

BP for hypertension

JVD

too much fluid removed

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4
Q

Too much fluid removed signs?

A

Hypotension

Tachycardia

dry mucous membranes

Dizziness

Skin tenting

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5
Q

Furosemide drug class?

A

Loop diuretic

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6
Q

Furosemide admin?

A

PO or IV

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7
Q

What is Furosemide for?

A

Great for pulmonary edema

Can be used with low GFR

CHF

hypertension

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8
Q

Furosemide labs?

A

BUN
electrolytes
Glucose

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9
Q

Furosemide assessment?

A

Swelling of extremities

Lung crackles

Short of breath

I&O

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10
Q

Special populations for Furosemide?

A

Children- Adverse effects can be sudden

Adults- prolonged use ok, chronic use teaching

OA- caution due to higher risk of cardiac/renal/liver impairment

Hepatic failure- used to treat ascites

Critically ill- severe edema in ICU

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11
Q

Furosemide adverse effects?

A

Ototoxicity

Decreased sodium, potassium, and fluid volume

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12
Q

Furosemide contras?

A

Sensitivity to drug

Anuria

Allergy to sulfonamides

Pregnancy unless benefits outweigh risk to fetus

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13
Q

Furosemide nursing considerations?

A

Caution in other nephrotoxic drugs

Can cause hyperglycemia

Decreased antibiotic effect

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14
Q

Furosemide admin?

A

IVP over 1-2 minutes (max- 20 mg/min) prevents ototoxicity

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15
Q

Furosemide teaching?

A

Potassium rich, low sodium diet

Dosage timing

Signs of fluid excess/deficit

Photosensitivity

Dizziness if used for hypertension

Caution with digoxin and diabetes meds

Daily weight

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16
Q

Hydrochlorothiazide drug class?

A

Thiazide diuretic

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17
Q

What is special about hydrochlorothiazide?

A

It’s not as strong as furosemide and is the 2nd choice diuretic

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18
Q

Hydrochlorothiazide uses?

A

Chronic edema in heart failure and nephrotic syndrome

Mild to moderate hypertension

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19
Q

How is hydrochlorothiazide given?

20
Q

What are labs to monitor with hydrochlorothiazide?

A

Fluid and electrolytes

Sodium levels

EKG

Glucose

21
Q

Special populations for hydrochlorothiazide?

A

Children: used for chronic lung disease

Used more often

Less side effects than adults

Older adults: caution due to more sensitivity to hypotension and electrolyte imbalances- use smallest effective dose

Hepatic impairment- risk of elevated ammonia levels

22
Q

What is important to know about hydrochlorothiazide regarding how long it takes to work?

A

They’re not as fast as loop diuretics

23
Q

Adverse effects of hydrochlorothiazide?

A

Hypotension

Dizziness

Bowel changes

Lowered sodium, potassium, and chloride

Hyperglycemia

Erectile dysfunction

24
Q

Contraindications for hydrochlorothiazide?

A

Sensitivity to sulfonamides

Anura

Pregnancy

25
Spironolactone drug class?
Potassium sparing diuretic
26
What is the MOA of spironolactone?
Reduces retention of sodium and water
27
What drug is k sparing and what does it mean?
Spironolactone Drug reduces urinary potassium loss
28
What is different about Spironolactone?
It’s a weak diuretic and often has to be used in combination with others
29
How long does Spironolactone take to work?
Takes day to take full effect
30
What are the uses for Spironolactone?
Heart failure Ascites in liver disease Hypertension Hypokalemia Hyperaldosteronism Hypertension
31
What are special population considerations for sprironolactone?
Children- take with food Discontinue in renal failure Caution with hepatic impairment Better diuretics in critical illness
32
Adverse effects of Spironolactone?
Dizziness, headache, abdominal cramping, diarrhea, Androgen receptor effects: deepening voice, gynecomastia, menstrual irregularity, testicular hypertrophy
33
Black box warning for Spironolactone?
Unnecessary use avoided Tumorigenic with chronic toxicity
34
Contraindications for Spironolactone?
Renal insufficiency First trimester pregnancy Caution with Dixogin and lithium
35
Spironolactone assessment?
Frequent BP and HR LOC abdomen assessment I&O Daily weight Decreased edema Fall risk assessment
36
Labs for spironolactone?
CMR and GFR
37
What increases the effects of Spironolactone?
Beta blockers- hyperglycemia Other drugs that raise potassium (hyperkalemia)
38
What decreases the effects of Spironolactone?
Alcohol Anti hypertensive drugs Salicylates
39
Spironolactone teaching?
No salt substitutes Risk of dizziness/drowsiness Risk of hypertension with drugs that raise potassium
40
What drug class is mannitol?
Osmotic diuretic
41
What part of the nephron does mannitol work?
Loop of henle and proximal convoluted tubule
42
How fast does mannitol work?
Very rapid diuresis
43
When is mannitol used?
When GFR is reduced For oliguria or anuria Cerebral edema Intraocular pressure Excretion of toxic substances (drug overdose) Can prevent renal failure by flushing kidneys of cellular debris
44
Mannitol assessment?
I&O daily weight Electrolytes capillary refill Edema
45
What are some nursing considerations for mannitol?
Does work with reduced GFR Very rapid fluid shift- risk of pulmonary edema, heart failure
46
What is a special consideration for Diphenoxylate/atropine?
Alcohol increases the sedative effect