DIT XIII: Psych Flashcards
Criteria for Dx of major depressive episode
5 symptoms + depressed mood/anhedonia for 2 weeks
“SIG E CAPS”: Sleep (hyper/hyposomnia), Interest, Guilt, Energy, Concentration, Appetite, Psychomotor retardation/agitation, Suicidal ideation
Features of atypical depression
Hypersomnia, hyperphagia, mood reactivity, hypersensitivity to rejection
Rx for atypical depression
SSRIs
Risk factors for suicide
“SAD PERSONS”: Sex (m), Age (teens and elderly), Depression, Prev attempts, EtOH, Rational thinking (decr), Sickness, Organized plan, No social support, Stated future intent
What is dysthymia
milder form of depression for at least 2 yrs
MOA of SSRIs
blocks reuptake of 5-HT
MOA of SNRIs
blocks reuptake of 5-HT and NE
MOA of TCAs
blocks reuptake of NE and 5-HT
MOA of MAOIs
inhibits MAO (which breaks down catecholamines, incl NE)
What is the MAOI washout period?
wait 2 wks after stopping MAOI before taking anything else
Name the class: fluoxetine, sertraline, paroxetine, citalopram, fluvoxamine
SSRI
Name the class: nortriptyline, imipramine, amitriptyline, desipramine, nortriptyline, clomipramine, doxepin
TCA
Name the class: selegiline, phenelzine, trancylcypromine
MAOI
Name the class: venlafaxine, duloxetine, milnacipram
SNRI
Name the class: mirtazapine, trazodone
Tetracyclic antidepressant
Which antidepressant has side effect of priapism
trazodone
Which antidepressant lowers the seizure threshold
bupropion, TCAs
Which antidepressant works well with SSRIs and increases REM sleep
trazodone
Which antidepressant is an appetite stimulant that is likely to result in wt gain?
mirtazapine
Antidepressant that can be used for smoking cessation
buproprion
Antidepressant that can be used for bedwetting in children
imipramine
Symptoms of TCA overdose
Coma, Convulsions, Cardiotoxicity (“Tri-Cs”)
+ resp depression, confusion
Symptoms of serotonin syndrome
Mental status changes, autonomic instability (CVS collapse, hyperthermia), neuromusc abn (musc rigidity)
What happens when you ingest tyramine while on MAOIs?
HTN crisis, hemorrhagic stroke, cardiac arrhythmias
Tyramine increases NE if no MAO enzymes
