DIT III: Pharm Basics Flashcards
0
Q
Eqn for volume of distribution
A
Vd = D / C
1
Q
What is Km
A
Km = [S] at 1/2 Vmax
Reflects enzyme’s affinity for substrate
2
Q
Eqn for loading dose
A
LD = Css x Vd
3
Q
Equation for clearance
A
CL = rate of elim / plasma conc
= 0.7 Vd / t1/2 = K x Vd
4
Q
Equation for maintenance dose
A
MD = Css x CL
5
Q
What are efficacy and potency
A
Efficacy: max effect of drug
Potency: amt of drug needed to get desired effect
