Disorders Of The Prostate Flashcards

1
Q

What is prostatitis?

A

Inflammation of prostate

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2
Q

What organisms cause acute + chronic prostatitis?

A

E. coli
Staphylococcus species
STIs pathogens

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3
Q

Describe acute prostatitis

A

Acute flare up of inflammation of prostate

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4
Q

Symptoms of acute prostatitis

A
  • malaise
  • rigors
  • fever
  • difficult passing urine
  • dysuria
  • perianal tenderness
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5
Q

What is found on a rectal exam of acute prostatitis?

A

Soft, tender + enlarged prostate

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6
Q

What does chronic prostatitis result from?

A

Inadequately treated infections
As antibodies cannot penetrate prostate effectively

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7
Q

Symptoms of chronic prostatitis

A

Asymptomatic

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8
Q

Diagnosis of chronic prostatitis

A
  • neutrophils, plasma cells + lymphocytes in histology
  • positive culture from sample of prostatic secretion
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9
Q

What is the most common type of prostatitis?

A

Chronic non bacterial prostatitis

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10
Q

Common history of patient with chronic prostatitis

A

Recurrent parasitic or urinary tract infections

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11
Q

What organism typically causes chronic non-bacterial prostatitis?

A

Chlamydia trachomatis

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12
Q

What is benign prostatic hypertrophy/hyperplasia?

A

Non-neoplastic enlargement of prostate gland

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13
Q

Presentation of BPH

A
  • difficulty or hesitancy to start urination
  • poor stream
  • dribbling post micturition
  • frequency
  • nocturia
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14
Q

Investigation of BPH

A

Digital rectal exam
Firm, smooth + rubbery prostate

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15
Q

Treatment of BPH

A
  • alpha blockers: relaxes smooth muscle at bladder neck + within prostate e.g.tamsulosin
  • 5a reductase inhibitors: prevents conversion of testosterone to dihydrotestosterone > shrinks prostate e.g. finasteride
  • transurethral resection of prostate
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16
Q

What can untreated BPH present with?

A

Acute urinary retention
Distended + tender bladder
Desperate urge to pass urine

17
Q

Differentiate the digital rectal exam findings of prostatitis, BPH + prostate cancer

A
  • prostatitis: soft, tender + enlarged
  • BPH: firm, smooth + rubbery
  • prostate cancer: hard + irregular
18
Q

Why is tamsulosin used in BPH treatment?

A
  • alpha blocker
  • inhibits binding of noradrenaline to prosthetic
  • causing prostate smooth muscle relaxation
19
Q

Why is finasteride used in BPH treatment?

A
  • 5a reductase inhibitor
  • prevents conversion of testosterone to dihydrotestosterone
  • ‘shrinks’ prostate