Disorders of Epidermal Maturation Flashcards
1
Q
ichthyosis
A
- looks like fish scales
- congenital ichthyosiform erythoderma (AR), lamellar ichthyosis (AR), x-linked ichthyosis, ichthyosis vulgarism (AD or acquired)
- build up of keratin, no basket weave pattern
- granulosum differences
2
Q
acute eczematous dermatitis
A
-allergic, primary irritant, atopic, drug-related
3
Q
contact dermatitis
A
- irrtant: direct toxic effects
- allergic: type IV HS rxn (nickel, poison ivy, mangos, iodine)
4
Q
-
-lichenification
A
- aka eczema
- worse in winter
- epidermal thickening
5
Q
nummular dermatitis
A
-coin shaped
6
Q
asteatoic dermatitis
A
- winter itch
- avoid excessive bathing
- use humidifiers
7
Q
acute spongiotic dermatitis
A
- spongiosis
- exocytosis
8
Q
erythema multiforme
A
- immune mediated HS rxn causing epidermal cell injury
- CD8 t cells
- symmetric, target lesions
- HSV, sulfa drugs, phenytoin, allopurinol
- can recur due to HSV
9
Q
stevens-johnson syndrome
A
- children
- mucous membranes, mouth, conjunctivae
- dysphagia, renal failure, convulsions
- bactrim, sulfa drugs
10
Q
toxic epidermal necrolysis
A
- more severe
- emergency
- detachment
- 30% mortality
- > 30% skin involved
- bactrim, sulfa drugs
11
Q
pityriasis rosea
A
- spongiotic dermatitis
- HSV7
- winter
- older children and young adults
- herald patch that looks like ringworm
- christmas tree pattern
12
Q
venous insufficiency
A
- incompetence causes increase hydrostatic pressure and capillary damage
- middle age and older adults
- valves
