Diseases of the nervous system Part 1

Question 1

CNS is consisted of

Answer 1

Brain and spinal cord

Question 2

Meningitis is inflammation of the

Answer 2

Meninges

Question 3

Encephalitis is inflammation of the

Answer 3

Brain

Question 4

CNS inflammation (2 types)

Answer 4

Meningitis and encephalitis

Question 5

Is meningitis or encephalitis more deadly?

Answer 5

Encephalitis

Question 6

Important Symptoms of meningitis

Answer 6

Neck stiffness and sensitivity to light

Question 7

Do meningitis need to be treated immediately?

Answer 7

YESSSSSs

Question 8

Is bacterial meningitis contagious?

Answer 8

YESSSSSS

Question 9

Is fungal and Protozoa meningitis contagious?

Answer 9

No

Question 10

Streptococcus agalactiae is acquired from

Answer 10

The mother’s birth canal
Most common cause of neonatal meningitis

Question 11

Hemophilus influenzae is Gram + or -

Answer 11

-ve

Question 12

Hemophilus influenzae shape

Answer 12

Rod

Question 13

Hib is type

Answer 13

B

Question 14

Meningitis vaccines are all ____ vaccines

Answer 14

Subunit

Question 15

Streptococcus pneumoniae causes (2)

Answer 15

Meningitis and pneumonia

Question 16

Streptococcus pneumonia shape and Gram

Answer 16

Diplococci and gram +ve

Question 17

You have 6 month child admitted to ER, non responsive, high fever, neck is stiff, what must you do?

Answer 17

Do a spinal tap and culture

Question 18

What is alpha hemolytic gram + diplococci Meningitis

Answer 18

Streptococcus pneumoniae

Question 19

Gram -ve diplococci meningitis

Answer 19

Neisseria meninitidis

Question 20

Neiserria meningitis significant sign

Answer 20

Rash on abdomen

Question 21

High risk places of neiserria

Answer 21

Military barracks, nursing homes, dorms
Crowded enclosed places

Question 22

Virulence factors for neiserria meningitis

Answer 22

Endotoxin
Fimbriae
IgA protease
Capsule (6 types)

Question 23

If the spinal fluid is clear what is it (generally)

Answer 23

Viral

Question 24

Lockjaw

Answer 24

Tetanus

Question 25

Clostridium tetani is + or -

Answer 25

+

Question 26

Is clostridium tetani spore forming?

Answer 26

Yes

Question 27

Tetanus neonatorum enters how

Answer 27

Throught cut stump of umbilical cord

Question 28

Do gram positive rods have endotoxins?

Answer 28

No!!!!!

Question 29

Does clostridium tetani get changed to a endotoxin or a exotoxin?

Answer 29

Exotoxin Because it is gram +

Question 30

Clostridum tetani is found on

Answer 30

Old, dirty, rusty objects

Question 31

Tetanus has a neurotoxin that codes for

Answer 31

Tetanospasmin

Question 32

You also need to administer what during treatment of tetanus?

Answer 32

Immunoglobulin

Question 33

3 viral diseases of nervous sytem

Answer 33

Poliomyelitis Rabies Arthropod-borne encephalitis

Question 34

Polio virus is in what family

Answer 34

Picornaviridae

Question 35

can we irradiate polio?

Answer 35

Yes

Question 36

How is polio transmitted

Answer 36

Oral-fecal route

Question 37

Are most cases of polio mild and asymptomatic?

Answer 37

Yes

Question 38

2% of polio cases are what

Answer 38

Paralytic polio Paralysis

Question 39

Is polio occurred in what month the most?

Answer 39

Mainly summer months Because people would go to public swimming pools

Question 40

Vaccine for polio (inactivated/killed)

Answer 40

Salk vaccine

Question 41

Oral polio vaccine (Live)

Answer 41

Sabin vaccine

Question 42

how were polio patients treated long ago

Answer 42

Iron lungs

Question 43

Remaining reservoirs of polio

Answer 43

Parts of Africa and asia

Question 44

Rabies family

Answer 44

Rhabdoviridae

Question 45

Shape and Gram of rabies

Answer 45

-ve, helical SsRNA

Question 46

Do we still vaccinate against polio?

Answer 46

Yes

Question 47

when would you get an oral polio vaccine?

Answer 47

Working in remote impoverished areas in other countries

Question 48

Transmission of rabies

Answer 48

Exposure to infected animals (Bites or handling)

Question 49

Rabies is shaped like a

Answer 49

Bullet

Question 50

Rabies CNS infection almost always leads to

Answer 50

Fatal encephalitis

Question 51

#1 animal with rabies

Answer 51

Bats

Question 52

Hydrophobia, convulsions, coma, agitation, spasms of the mouth, salivation What is it?

Answer 52

Rabies

Question 53

When is it too late to treat rabies?

Answer 53

Once symptoms appear

Question 54

Diagnosis or rabies

Answer 54

Prescience of virus in brain slices by observing negri bodies on autopsy

Question 55

Why is fear of water a symptom of rabies?

Answer 55

Because when you see water you start to salivate and that is extremely painful for them.

Question 56

Rabies is most of the time not confirmed until when

Answer 56

Death

Question 57

Negri bodies

Answer 57

Viral inclusion bodies in brain

Question 58

Passive treatment of rabies

Answer 58

HRIG Human rabies immunoglobulin

Question 59

When would you get regular rabies vaccines?

Answer 59

If you work with animals Park ranger, vet, etc.

Question 60

What is significant feature of the rabies vaccine?

Answer 60

One of the few diseases that you can vaccinate post exposure It takes many weeks for the virus to reach the brain

Question 61

Killed viral vaccine of rabies

Answer 61

HDCV = human diploid cell vaccine

Question 62

Prevention of rabies

Answer 62

Vaccinate domestic and wild animals

Question 63

When is the symptoms the fastest for rabies?

Answer 63

When its closer to the brain

Question 64

Jeanna Giese

Answer 64

Rabies survivor Vegetative state- later recovered