Diseases of the equine proximal GI tract Flashcards

1
Q

Dyspahgia

A

Difficulty with/inability to swallow

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2
Q

Why is dysphagia a problem

A

Lack of adequate nutritional intake

Secondary aspiration pneumonia

Welfare

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3
Q

Prepharyngeal dysphagia

A

Dropping feed, hypersalivation, cannot prehend feed

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4
Q

Pharyngeal and post-pharyngeal dysphagia

A

Coughing, nasal discharge (food/water), neck extension when swallowing

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5
Q

Potential painful causes of dysphagia

A

Dental abscesses

Temporohyoid osteoarthropathy

Foreign bodies, trauma

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6
Q

Potential obstructive causes of dysphagia

A

Oesophageal obstruction

Retropharyngeal abscess

Thyroid mass

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7
Q

Potential neurological causes of dysphagia

A

Forebrain or brainstem disease

Prehension: CN V, VII, XII

Transfer of bolus to pharynx: CN V, XII

Swallowing: CN X (and IX? Disproven?)

Neuro/muscular disease e.g.:
* Guttural pouch disease (strangles, mycosis, etc.)
* Grass sickness
* Botulism
* Megaoesophagus
* Hyperkalaemic periodic paralysis

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8
Q

Media compartment of guttural pouch

A

Internal carotid artery

Fold containing CN IX, XI, XII; CN X ventrally

Cranial sympathetic ganglia

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9
Q

Lateral compartment of guttural pouch

A

External carotid and maxillary arteries

CN VII, VIII, and mandibular branch V near wall

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10
Q

Clinical signs of oesophageal obstruction

A

Head and neck outstretched

Food from nostrils

Coughing

Distressed or very quiet
§ Occasionally mistaken for colic

Some horses panic

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11
Q

Risk factors for oesophageal obstruction

A

Poor dentition

Rapid ingestion dry feed

Eating when heavily sedated

Underlying oesophageal disease
§ Diverticula
§ Abscesses
§ Neoplasia
§ Functional disease

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12
Q

DIagnosis of oesophageal disease

A

Palpate neck (left)
§ May feel impacted bolus of food

Pass nasogastric tube (carefully)

Endoscopy
§ Likely to be performed in complicated cases that are not resolving
§ Not expected on first opinion initial visit

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13
Q

Treatment of oesophageal obstruction

A

Tell owner to take feed away

Sedate (heavily)
§ Head must be low

Buscopan?
§ Smooth muscle relaxant – distal oesophagus

Oxytocin?
§ Smooth muscle relaxant – proximal oesophagus

Pass nasogastric tube

Gentle lavage with plain water
§ This tends to work best for feed matter

Endoscopy if not resolving, may require referral

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14
Q

Management of oesophageal obstruction

A

Warn owner regarding aspiration pneumonia risk
§ Antimicrobials – I would select doxycycline (on cascade)

Check teeth

Check diet

Sloppy feed for 48 hours – easily palatable and swallowed. Start to reintroduce longer fibre length after this if the horse is managing well

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15
Q

Sequellae to oesopahgeal obstruction

A

Secondary aspiration pneumonia
§ Can be severe/fatal
§ Prophylactic antimicrobials

Oesophageal ulceration
§ Some vets will give sucralfate to cases with moderate-severe ulceration

Oesophageal diverticula

Oesophageal rupture
§ Very bad prognosis, esp. if in thorax

Stricture formation

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16
Q

Presentation of equine gastric ulceration syndrome (EGUS)

A

Variable presentation
○ ‘fussy eating’
○ ‘girthy’
○ ‘grumpy’
○ Poor performance
○ Poor coat condition
○ Weight loss/poor condition
○ Bruxism
○ Low grade colic

17
Q

Two types of EGUS

A

Categorised according to which anatomic portion of the stomach affected

Equine squamous gastric disease (ESGD)

Equine glandular gastric disease (EGGD)

May have ESGD, or EGGD, or both.

No correlation.

Diagnosis: Gastroscopy

18
Q

ESGD

A

Equine squamous gastric disease

Commonly at margo plicatus, lesser curvature

RIsk factors: exposure of squamous mucosa to acid, starchy diet, stress, fasting

Treat with omeprazole

19
Q

EGGD

A

Equine glandular gastric disease

Pathophysiology unknown

Treat with omeprazole and sucralfate or misoprostol

20
Q

Management of EGUS

A

Diet

Low starch

High fibre, access to forage

Add oil

Calories if required

Reduces gastric acid production??

Alfalfa

Turnout as much as possible

EGGD: at least two rest days/week

21
Q

Gastric impaction

A

Uncommon cause of colic

Feedstuff that swells

Dysmotility disorders
§ Consider liver disease

Outflow tract obstructions

22
Q

Gastric neoplasia

A

Squamous cell carcinoma
§ Very poor prognosis, not very common

Adenomatous polyps
§ May cause outflow tract obstruction if large, or be associated with ‘ulceration’

23
Q

Four recognised conditions of inflammatory bowel disease

A

Granulomatous enteropathy

Multisystemic eosinophilic epitheliotrophic syndrome

Lymphocytic plasmacytic enteropathy

Eosinophilic colitis

24
Q

Clinical signs of IBD

A

May affect other body systems

Most common sign reported: weight loss in face of good appetite

Mild recurrent colic

Chronic or intermittent diarrhoea

25
IBD diagnosis
Check diet, exclude dental disease, parasitism etc., routine blood work Abdominal ultrasound, abdominocentesis Glucose absorption test Biopsies § Duodenal § Rectal Laparotomy/laparoscopy?
26
Oral glucose absorption test for IBD
Easy to do in first opinion practice ○ Starve 12 h ○ Baseline blood sample for glucose ○ 1g/kg glucose as 20% via nasogastric tube ○ Blood sample at 0, 30, 60, 90, 120, 150, 180, 210, and 240 min Normal: >85% increase Partial failure: 15-85% increase Total failure: <15% increase
27
Treatment of IBD
Corticosteroids Limited evidence for other treatments such as azathioprine Ensure good parasite control ○ Concern RE trigger for inflammation Diet ○ Highly digestible, high fibre ○ Oil ○ Feed smaller meals more frequently
28
Lymphoma - GI disease in horses
Young horses ○ Although any age may be affected Similar diagnostic approach as IBD Rectal biopsy and peritoneal fluid analysis may aid diagnosis, but can be challenging Guarded prognosis
29
Duodenitis-proximal jejunitis
Clinical signs mimic small intestinal obstructive diseases We do not understand aetiopathogenesis Increased secretion -> small intestinal distension/reflux May have secondary hepatic changes Peritoneal fluid analysis: lower TNCC than strangulating SI lesions