diseases final ( canine parvovirus) Flashcards
what is the etiology
CPV-2
what is the definition of canine parvovirus
an acute highly contagious enteritis of dogs (especially in young puppies that do not have enough immunity to resists this infection)
CPV-2 is _________ In the environment worldwide
prevalent
how long does this virus survive outdoors
this virus survives and remains infectious in the environment for many months
what is this virus resistant to
sunlight, drying, and most disinfectants
what are the three antigenic variants of CPV 2 that are pathogenic to dogs
2a, 2b, 2c
how does transmission occur
Feco-oral route
how and where does the virus replicate
viral replication occurs in tonsilar lymphoid tissue initially- this is followed by spread of the virus to other lymphoid tissue - the virus then spreads to the blood stream- from the bloodstream the virus spreads to the predilection tissues (intestinal crypt cells, bone marrow, lymphoid tissues)
what time does the viremia occur
viremia occurs by day 3-5 postinfection and precedes clinical signs
what happens after the viremia occurs
fecal shedding occurs soon after viremia, with large amounts of virus excreted in feces in clinically affected dogs
where is the virus shed
virus is shed in the feces and usually lasts no longer than day 12 postinfection
what two things are the usual source of contaminated feces
fomite
environmental
what is the incubation period
5 days or 5-10 days
what is the most susceptible age group for developing severe clinical illness
6 weeks to 16 weeks
how long may the puppy remain susceptible after 16 weeks
may remain susceptible up to 6 months of age (in this age group puppies that become clinically ill from CPV infection will generally get a milder form of the clinical illness because they have some partial immunity)
