Diseases Flashcards
Diphtheria
-CDC recommends vaccine for all ages
-Transmitted person to person
-Acute Toxin medicated disease caused by corynebacterium diphtheriae
Causes:
-difficulty breathing
-heart failure
-paralysis
-Death
Diphtheria clinical Features
- May involve mucous membrane
- Classified based on site of disease
- Pharyngeal and Tonsillar Diphtheria
- Insidious onset of pharyngitis
- Membrane may cause respiratory obstruction
- Fever usually not high but patient appears toxic
Haemophilus influenza type B (HIB)
- Requires hospitalization for invasive HIB disease
- Bacterial infection
- gram negative coccobacillus - transmission is by respiratory droplet spread
Common invasive disease that are caused byH. Influenza type B
- meningitis
- epiglottis
- pneumonia
- arthritis
- cellulitis
Hepatitis A
- caused by infection with HAV (transmitted through ingestion of contaminated food and water or through direct contact with an infectious person)
-inflammation of the liver
Causes:
-fever
-malaise
-anorexia
-nausea
-abdominal discomfort
-dark urine
-jaundice
Hepatitis A clinical features
- illness not specific for hepatitis A
- Likelihood of symptomatic illness directly related to age
- children generally asymptomatic, adults symptomatic
Hepatitis B
- indistinguishable from other types of acute viral hepatitis
- Transmitted by contact with blood or body fluids of an infected person
hepatitis B clinical features
- Incubation period 45-160 days (average 120 days)
- Nonspecific prodrome of malaise, fever, headache, myalgia
- At least 50% of infections asymptomatic
Hepatitis B complications
- Fulminant hepatitis: Development of hepatic failure and encephalopathy within 2 weeks of onset of jaundice.
- Hospitalization
- Cirrhosis: degeneration of cells, inflammation and fibrous thinking of tissue
- Hepatocellular carcinoma (liver cancer)
- Death
Human papillomavirus (HPV)
- transmitted sexually
- most HPV infections are asymptomatic
- can cause cancer later
HPV vaccine
-Gardasil (6, 11, 16, 18)
Gardasil vaccine 6, 11
Low grade cervical cell changes
Gardasil vaccine 16,18
High grade cervical cell abnormalities that are precursors to cancer, and anogenital cancers
Influenza
- transmitted from person to person via respiratory droplets
- highly infectious viral illness
Influenza Virus Type A
Moderate to severe illness
- all age groups
- humans and other animals
Influenza virus type B
Milder disease
- primarily affects children
- humans only
Influenza virus Type C
Reported in humans
-no epidemics
Influenza Clinical Features
- incubation period 2 days (range 1-4days)
- 50% of infected persons develop classic symptoms
- abrupt onset of fever, myalgia,sore throat, nonproductive cough,headache
Influenza Compliations
- pneumonia
- Reye syndrome
- Myocarditis
- Asthma
- Encephalitis
- myositis
- organ failure
- death rates are not exactly known
- Reported at about average of 36,000 US cases annually
- GET VACCINATED!
Measles
- Acute viral infectious disease
- Respiratory transmission virus
Measles Clinical Features
- Incubation period 10-12 days
- Prodrome 2-4 days
- stepwise increase in fever to 103 F-105 F
- cough, conjunctivitis Koplik spots (rash on mucous membranes) - Rash
- 2-4days after prodrome
- 14 days after exposure
- persist 5-6 days
- begins on face and upper neck
- maculopapular, becomes confluence
- fades in order of appearance
Measles Complications
Diarrhea 8% Otitis media 7% Pneumonia 6% Encephalitis 0.1% Seizures 0.6-0.7% Death 0.2%
Meningococcal disease
- Severe acute bacterial infection
- case fatality ratio of meningococcal disease is 10% to 15% even with appropriate antibiotic therapy
Meningococcal Meningitis
Most common presentation of invasive disease
CLINICAL FINDINGS
- fever
- headache
- stiff neck
Mumps
- Acute viral illness
- Transmission is direct and droplet
Mumps clinical features
- incubation period 12 to 25 days
- Nonspecific prodrome of myalgia, malaise, headache, low grade fever
- Parotitis in 9%-94%
Mumps complications
- Orchitis
- Pancreatitis
- Unilateral Deafness
- Death