Disease/Neoplasm Associations

Question 1

acanthosis nigricans

Answer 1

visceral malignancy (esp stomach)

Question 2

actinic keratosis

Answer 2

skin SqCC

Question 3

AIDS

Answer 3

aggressive malignant lymphomas (non-Hodgkin);

Kaposi sarcoma

Question 4

AI diseases (e.g. Hashimoto thyroiditis, SLE)

Answer 4

lymphoma

Question 5

Barrett esophagus

Answer 5

esophageal adenocarcinoma

Question 6

chronic atrophic gastritis, pernicious anemia, postsurgical gastric remnants

Answer 6

gastric adeocarcinoma

Question 7

cirrhosis

Answer 7

HCC

Question 8

Cushing syndrome

Answer 8

lung SCC

Question 9

dermatomyositis

Answer 9

lung cancer

Question 10

Down syndrome

Answer 10

acute leukemias (ALL/AML)

Question 11

dysplastic nevus

Answer 11

malignant melanoma

Question 12

hypercalcemia

Answer 12

lung SqCC

Question 13

immunodeficiency states

Answer 13

malignant lymphoma

Question 14

Lambert-Eaton myastenic syndrome

Answer 14

lung SCC

Question 15

myasthenia gravis, pure RBC aplasia

Answer 15

thymoma

Question 16

Paget disease of bone

Answer 16

2’ osteosarcoma & fibrosarcoma

Question 17

Plummer-Vinson syndrom

Answer 17

esophageal SqCC

Question 18

polycythemia

Answer 18

RCC, HCC

Question 19

radiation exposure

Answer 19

leukemia, PTC, breast cancer

Question 20

SIADH

Answer 20

lung SCC

Question 21

tuberous sclerosis (facial angiofibroma, seizure, intellectual disability)

Answer 21

giant cell astrocytoma, renal angiomyolipoma, cardiac rhabdomyoma

Question 22

ulcerative colitis

Answer 22

colonic adenocarcinoma

Question 23

xeroderma pigmentosum, albinism

Answer 23

melanoma, basal cell carcinoma, ESPECIALLY skin SqCC