Disease and Immunity Flashcards
Define disease
?any condition which impairs any normal bodily functions except those caused by bodily injury.
Each disease has a recognisable cause and produces symptoms
What are the two types of diseases
Infectious and Non-Infectious
Define an infectious disease
disease which cannot be spread from one individual to another
includes genetic and lifestyle-caused diseases
Define a Non-Infectious disease
diseases cause by another organism (pathogens): these diseases can be transmitted from one organism to another
What is the difference between a cellular and non-cellular disease?
a non-cellular disease requires host to survive. A host cell supplies the necessary organelles fro a non-cellular agent to reproduce
a cellular disease can be single or multi-cellular, and are able to reproduce on their own
Define Prions
misfolded infectious proteins that can propagate by causing misfolding in the original protein type
Spread by eating contaminated meat or cannibalising brain tissue
Define Viruses
Viruses are infectious agents that infect living cells and use the cells replication machinery to copy themselves
Define Bacteria
single-celled prokaryotic organisms. The vast majority of bacteria are harmless and necessary for life on earth
bacteria can cause disease by entering a host and adversely affect tissue and can produce toxins
Define Fungal diseases
rare in animals, but can cause infections that are long lasting and difficult to treat
they spread by spores and are generally chronic
Define a pathogen
any disease-producing agent, especially a virus, bacterium, or other microorganism
What is the difference between non-specific defence and specific defence?
non-specific defences are general mechanism that try to protect against all and any pathogens, while specific defences mechanisms that defend against specific pathogens
Outline the First line of defence
Non-specific. Physical and chemical barriers
eg- skin, tears, mucus and saliva
Outline the Second line of defence
Non-specific. Utilised in the event of the failure of the first line of defence
White-blood cells are the most common form of second-line defence
What are some Second-line mechanisms of defence?
White-Blood Cells, Phagocytes, inflammation, fever and blood clotting, neutrophils, natural killer cells, compliment proteins and interferons
Define White Blood Cells
Also called Leukocytes. Produced in the bone-marrow and carried in the blood
Neutrophils (phagocytes), Eosinophils (detoxify foreign particles), Basophils (produce histamine), lymphocytes (produce antibodies) and Monocytes (develop into macrophages)