Disease and Conditions of blood, lymph and immune system Flashcards
Disseminated Intravascular Coagulation (DIS)
Abnormal activation of the proteins involved in blood coagulation
Causes small blood clots to form in vessels and cutting off supply of oxygen to distal tissues
Graft Rejection
Process in which a recipient’s immune system attacks a transplanted organ or tissue
Graft versus host Disease (GVHD)
Complication that occurs following a stem cell or bone marrow transplant in which the transplant produces against recipient’s organs that can be severe enough to cause death
Hematoma
Localized accumulation of blood, usually clotted, in an organ, space or tissue due to a break in or severing of a blood vessel
Hemoglobinopathy
Any disorder caused by abnormalities in the hemoglobin molecule
Lymphadenopathy
Any disease of the lymph nodes
Lymphadema
Swelling, primarily in a single arm or leg, due to an accumulation of lymph within tissues caused by obstruction or disease in the lymph vessels
Multiple Myeloma
Malignant tumor of plasma cells (cells that help the body fight infections by producing antibodies) in the bone marrow
Sepsis
Presence of bacteria or their toxins in the blood; also called septicemia or blood poisoning
Systemic Lupus Erythematosus (SLE)
Widespread autoimmune disease that may affect the skin, brain, kidneys and joints and causes chronic inflammation; aka discoid lupus if symptoms are limited to the skin
Thrombocythemia
Overproduction of platelets leading to thrombosis or bleeding disorders due to platelet malformations
Thrombocytopenia
Abnormal decreased in platelets caused by low production of platelets in bone marrow or increased destruction of platelets in the blood vessels (intravascular), spleen (extravascular) or liver (extravascular)
Von Willebrand Disease
Bleeding disorder caused by a deficiency of von Willebrand factor, a “sticky” protein that lines blood vessels and reacts with platelets to form a plug that leads to clot formation
