Dipyrimidines and Sulphonamides Flashcards
1
Q
Name examples of D&S
A
Trimethoprim and co-trimoxazole
2
Q
What can D&S be used for?
A
UTI and RTI and shingellosis
3
Q
Whats the main S/E of D&S?
A
Steven Johnsons syndrome , blood disorders and bone marrow suppression
so if someone experiences bruising or bleeding on trimethoprim - they need to be referred
4
Q
What are the signs and symptoms of steven johnsons syndrome?
A
Hives Facial Swelling Tongue Swelling Shedding of skin Red/purple rash
5
Q
What would you monitor if patients are on D&S?
A
Blood count especially patients taking long term therapy
Maintain adequate fluid intake
6
Q
When should trimethoprim be avoided?
A
in pregnant women (especially 1st trimester)
