Digestive: Viral Dss (part 1) Flashcards
Viral diseases
- Inclusion body hepatitis
- Malabsorption syndrome
- Other viral enteritic infections
a. Hemorrhagic enteritis
b. Turkey Coronavirus Enteritis
c. Rotavirus infection - Viral infection of Waterfowl
a. Duck hepatitis
b. Duck virus enteritis
c.Hemorrhagic nephritis and enteritis of.
geese - Goose parvovirus infection/Derzy’s disease
Inclusion body hepatitis etiologic agent
Avian adenovirus
Disease o young chickens
-hemorrhages
-pale bone marrow
- anemia
- depression
Inclusion body hepatitis
Sudden onset of mortality peaking in 3-4 days and continuing for 2-3 weeks
Inclusion body hepatitis
Inclusion body hepatitis incubation period
24-48 hours
Low morbidity,
MT reaches 25% over a 2 week period (course of disease)
Inclusion body hepatitis
Normally seen in meat producing birds at 3-7 weeks
Inclusion body hepatitis
Could occur in younger and older birds (breeder flock)
Inclusion body hepatitis
Inclusion body hepatitis transmission
Horizontal and vertical transmision
-Pale carcass, punctuate hemorrhages on breast muscles
-Swollen liver w/ subcapsular speckled hemorrhages and necrotic foci (punctuate not stellate)
-Anemia due to degeneration of bone marrow (pale on necropsy)
Inclusion body hepatitis
Inclusion body hepatitis diagnosis:
-Clinical signs and lesions
-Pathognomonic: demonstration of basophilic inclusion bodies of hepatocytes
-Isolated by inoculation in SPF (specified pathogen free) embryos or eggs with liver homogenates
Cowdry type A inclusion bodies in nucleus
Inclusion body hepatitis diagnosis: Pathognomonic
Inclusion body hepatitis tx and prevention
-Antibiotics to prevent bacterial infection
-Obtain stocks from IBD-vaccinated flocks
-Contaminated poultry house should be disinfected with compounds
-Vaccination
Tx: little value because self limiting (2weeks)
Inclusion body hepatitis
Inclusion body hepatitis:
Contaminated poultry houses should be disinfected with _________________
with iodine-containing compounds for NaOCl (sodium hypochloride)
Running/stunting syndrome
Malabsorption syndrome
Malabsorption syndrome etiologic agent
Avian Reovirus
Helicopter wing syndrome
Malabsorption syndrome
Infectious proventriculus
Malabsorption syndrome
Pale bird disease
Malabsorption syndrome
Brittle bone disease
Malabsorption syndrome
Seen in birds 6 weeks
also in chicks 7-14 days after hatching
Malabsorption syndrome
Malabsorption syndrome
Mortality
Morbidity
Mt: 2-10%
Mb: 5-50%
Poor FCR
Uneven growth rates
Reduced marketability of affected birds
Feed Efficiency and Rate of Gain Decreases in Malabsorption Syndrome
Malabsorption syndrome transmission
Horizontal and vertical transmission
Undigested feeds in feces
Malabsorption syndrome
Seen in bilateral swelling of shanks and above the hocks: birds walk with stilted gaits
Malabsorption syndrome: Tenosynovitis in 4-8 weeks old
Lesions:
GIT- atrophy if villi, proventriculus gizzard, enteritis
Arthritis- myocarditis, encephalimalacia, hepatitis, osteoporosis, pancreatitis
Malabsorption syndrome
Malabsorption syndrome diagnosis
-Test: AGPT (agar gel precipitation test), virus neutralization test to detect specific serotypes
-Isolated: inoculate GIT homogenates from infected chicks into embryonated chicken eggs 5-7 days old
Malabsorption syndrome prevention and control
-strict sanitation
-vaccinate day old chicks
-vaccinate breeder flocks to transmit passive immunity
Etiologic agent for hemorrhagic enteritis
Type II Avian Adenovirus
Causes marble disease in pheasants
Hemorrhagic enteritis
Acute viral dss of turkeys 4 weeks and older
Hemorrhagic enteritis
Hemorrhagic enteritis natural host
Turkeys, pheasants, chickens
Financial losses+ immunosuppression and subsequent secondary bacterial infection
Hemorrhagic enteritis
Rapid onset progression of clinical signs over 24 hrs period (acute onset)
Hemorrhagic enteritis
Hemorrhagic enteritis transmission
Feco-oral route (horizontal)
-Depression, melena, bloody droppings, death in 24 hrs of recovery
-Respiratory compromise: progressive dyspnea
Hemorrhagic enteritis
Post mortem lesions: pale carcass in good condition
Hemorrhagic enteritis
Pheasants: enlarged, mottled (marbled) spleen and edematous congested lungs
Hemorrhagic enteritis
Friable spleen
Hemorrhagic enteritis
Congested lungs, enlarged livers with petechial hemorrhages
Hemorrhagic enteritis
Hemorrhagic enteritis diagnosis
-Isolation and ID (identification) of virus
-Serology: AGPT, ELISA
Hemorrhagic enteritis differential diagnosis
-Reticuloenotheliosis of lymphoproliferative
-Bacterial septicemic diseases
Tx for hemorrhagic enteritis
-Convamescent antiserum 0.5-1ml
-Antibiotics for secondary bacterial infection
Control and prevention for hemorrhagic enteritis
-Good biosecurity
-Vaccination
Bluecomb disease
Turkey coronavirus enteritis
Mud fever
Transmissible enteritis
Coronaviral enteritis
Turkey coronavirus enteritis
Etiologic agent for turkey coronavirus eneteritis
Group 3 Coronavirus
Acute highly contagious dss of turkeys
Turkey coronavirus enetritis
Incubation period of bluecomb dss
1-5 days (ave. 2-3 days)
Shed in feces for several weeks after recovery from clinical disease
Bluecomb dss
Sudden onset of clinical signs with high MB
Bluecomb dss
Bluecomb dss transmission
Feco-oral route (horizontal)
-decrease water consumption
-Watery diarrhea, dehydration, hypothermia, weight loss
- droppings: green to brown, watery, frothy with mucus and urates
Bluecomb dss
Lx in intestine and bursa of fabricious
Bluecomb dss
-Duodenum and ileum are pale and flaccid
-Ceca distended and filled with watery content
Bluecomb disease
Bluecomb disease diagnosis
-virus isolation
-FAT, RT-PCR
-Serology
Bluecomb disease: Tx and prevention
-antibiotics for secondary bacterial infection
-biosecurity measures
-thorough cleaning and disinfection
-Depopulation
-Downtime for min of 3-4 weeks
Major dss of young ducklings
Duck hepatitis
Etiologic agent for duck hepatitis
Duck hepatitis types 1,2,3
Economic importance to all duck growing farms
Duck hepatitis
Highly fatal, rapidly spreading viral infection
Duck hepatitis