Digestive System Module 4 Flashcards
The function of taking in food is called
Ingestion
What are the two functions of Digestion
1st Chemical Digestion (Enzymes breaking of covalent bonds)
2nd Making big pieces of food smaller
The function of chemically transferring digested molecules from the g.i. tract to be absorbed in the body/bloodstream is called
Absorption
The function of removing undigested molecules (Defecation) from g.i. tract
Elimination
Tube like structure that extends from the mouth to the anus
G.I. Tract
Secrete digestive enzymes into g.i. tract
Exocrine glands
What are the accessory organs of the GI tract
Salivary glands, liver, gallbladder, and pancreas
side:Exocrine Glands
Which layer is the innermost in the wall of the g.i. tract
Mucosa
What are the functions of Mucosa
Mucous membrane (goblet cells)
Protects underlying tissues
Many secretory cells (digestive juices) are found in the mucosa
What do goblet cells make
Mucous
What is the 2nd layer (G.I. Tract) to innermost layer called
Submucosa
What is the Submucosa made out of
Connective tissue
What does the Submucosa contain
Blood vessels, Nerves, in the small intestine it contains many mucous secreting glands
What does the Submucosa do
Regulates activity of g.i. tract against acid
What is the 3rd layer of the GI Tract wall called
Muscle
What are the two subdivisions of the Muscle layer called
Inner layer and Outer layer
What is the muscle layer made out of
Muscle
Describe the inner layer of Muscle layer
has fibers that are arranged in a circular pattern (contraction narrows the lumen)
Describe the outer layer of Muscle layer
has fibers that are arranged in a longitudinal pattern (contraction makes the g.i. tract shorter)
The combination of the inner muscle layer and the outer muscle layer produces
Peristalsis
The stomach has an extra layer that is referred to as the
The oblique layer
The oblique layer is responsible for
Strengthens the stomach and help it with mixing food and digestive enzymes. HELPS STOMACH WITH CHURNING
The 4th layer of the GI Tract is called
Serosa
The visceral layer of the peritoneum is
Serosa
The esophagus is covered with
Fibrous connective tissue
Projections hold
relative position
Peritoneal Membranes form a
Large flat Folded Structure
Describe the functions of the Peritoneal Membranes (2)
Helps anchor the digestive organs
Separates the abdominal cavity into compartments which help restrict the spread of infection
What do the Peritoneal Membranes contain
Blood vessels, Lymph vessels, and nerves
In relation to the Peritoneal Membranes, the digestive organs are the _______ and ________, the membranes in front are the _________ and ________ ________.
Mesentary and Mesocolon
Greater and Lesser Omentum
The ORAL CAVITY is also referred to as the
The Mouth
The process of putting food in mouth is called
ingestion
The function of chewing food in our mouth is called
Mastication
When does the beginning of mechanical digestion occur
During Mastication
During mastication what lubricates food
Saliva (Salivary Amylase)
Swallowing or moving appropriate amounts of food toward larynx is called
Deglutition
What covers the pharynx during Deglutition
Uvula
What separates the oral cavity from the nasal cavity
Soft and Hard Palate
The Maxillae is
Upper jaw
The Mandible is
Lower jaw
The ridges between each tooth is called
gingiva
The mandible is famous for being
The only movable bone in the skull
The tongue is a ______ organ that is anchored by the _____ to the floor of the mouth
Muscular
Frenulum
What are the functions of the tongue
taste buds, helps with chewing, swallowing, and speech
Sublingual Capillary Bed
??????
What are the 3 pairs of Salivary Glands called
Parotid, Submandibular, and Sublingual
The largest pair of Salivary Glands, right by the ears
Parotid
Salivary Gland directly under jawbone
Submandibular
Salivary gland under the tongue
Sublingual
What are the functions of Saliva
Moistens food to help with Mastication and Deglutition
Helps keep mouth and teeth clean …lysozyme
Amylase converts starch to sugar
What is lysozyme
an enzyme that catalyzes the destruction of the cell walls of certain bacteria, occurring notably in tears and egg white.
What are the teeth made of
Dentin (Calcium Based)
The crown of the tooth is covered with
Enamel
What does the root of the tooth under the gumline do
Anchors the tooth in the jaw
What are the accessory structures of the Mouth (3)
Tongue, Salivary Glands, Teeth
Over the course of time a person will have two sets of teeth the ______ are the first and have __total
Deciduous 20 total
The 2nd set of teeth we get are called _______ and __ total
Permanent 32 total
The common passageway for respiratory and GI systems
Pharynx, Oral Cavity, Laryngyl Pharynx
During Deglutition what is the tongue responsible for
pushing bolus of food mixed with saliva into the pharynx
What particular part of the Pharynx does the uvula close during swallowing
Naso-pharynx
What covers the Larynx during swallowing
Epiglottis
The esophagus is a _______ tube about ______ long
Muscular
10 inches
What is the function of the esophagus
Moves food mixed with mucus by peristalsis into the stomach
Where does the esophagus travel through
Esophageal hiatus in the diaphragm before it reaches the stomach
The stomach is located in which quadrant
Left upper quadrant
What are the functions of the stomach (3)
Food storage
Churn
Digestion
During digestion in the stomach what gets absorbed
HCI (Hydrochloric Acid)
Pepsin
The stomach is a ___ shaped Organ
J shaped
The stomach contains 2 ______
sphincters
The two types of sphincters are called the
Cardiac Sphincter and the Pyloric Sphincter
The cardiac sphincter is at the _______ and he Pyloric sphincter is at the _______
Entrance of stomach
Exit
Both sphincters are _______ when the stomach churns
closed
_____ helps the stomach stretch
Rugae
The 3 layers of the stomach are
Circular, Longitudinal, and Oblique
When the stomach is empty it has folds called the
Rugae
The 3 REGIONS of the stomach are
Fundus
Body
Pylorus
Pylorus contains
secretory cells
Gastric pits are located in the
Stomach
Goblet cells are located in the
Gastric pits
Chief cells located in the ________ make _________
Gastric pits Digestive enzymes (Pepsin)
Parietal cells located in the Gastric pits make (2)
HCI Intrinsic Factor(b12)
Secretions of the gastric pits are called
Gastric juice
The nervous control of the stomach activity is done by
The Vagus Nerve
The Parasympathetic Nervous System Nerve
Vagus Nerve
Hormonal control is influenced by
Gastrin produced by G cells in the stomach
Gastrin is produced in the stomach in response to
Stomach distention
Presence of caffeine in the stomach
Presence of partially digested protein in the stomach
What are the functions of gastrin (2)
Secretion of large amounts of gastric juice
Closure of the cardiac sphincter
Food leaves the stomach in the form of _______ and it is _____
Chyme
Highly acidic
Food leaves through the stomach through the _________ and enters the _________
Pyloric sphincter
Small intestine
The largest part of the digestive tract is the
Small intestine
The small intestine is about _______ long and about ____ in diameter
20 inches
1 inch
The small intestine is folded and has millions of finger like projections called _____ which _____
villi
increases the surface area for absorption
The small intestine with help of the VILLI absorb
Fat and Fat soluble vitamins
Each villus contains (2)
Blood capillaries and a lacteal
The first part of the Small intestine is the ______ and it is _____ inches long
Duodenum
12 inches
The duodenum is __ shaped
C
Describe the functions of the Small Intestine
Receive Chyme from the Stomach and Digestive Secretions from the Liver and Pancreas
What protects the small intestine from acidic chyme
Mucous secreting glands
Most digestion and absorption takes place in the
Duodenum
The 2nd part of the Small Intestine is the _____ and is about ______ long
Jejunum
8 FOOT long
What takes place in the Jejunum
Some digestion and absorption
The 3rd part of the Small Intestine is the _____ and it is _____ long
Ilium
12 FOOT LONG
The Ilium ends at the
ileocecal valve
The Ilium contains _____ that
Peyer patches (Patches of lymphatic tissue) prevent normal flora from the large intestine to small intestine
What are the four enzymes secreted by the small intestine
Lactase
Sucrase
Maltase
Peptidases
Function of lactase
digest lactose (sugar in milk)
Function of Sucrase
digest sucrose (table sugar)
Functions of Maltase
digests maltase (digestion of grains)
Functions of Peptidases
coming from the stomach with chyme
digests Pepsin, HCI
BEGGINING OF PROTEIN IN STOMACH
What are the 3 enzymes and the 1 sodium secreted by the pancreas
Pancreatic Amylase
Pancreatic Lipase
Pancreatic Enzymes (tripsin + chymotripsin)
Sodium Bicarbonate
Bile is secreted by the
Liver
Function of Pancreatic Amylase
Carb/Starch digestion
Function of Pancreatic Lipase
Lipids
Function of Pancreatic Enzymes (Tripsin + Chymotripsin)
Proteins
Bile is the
breaking down or large particles of fat so it can be digested
The Large intestine is about ______ long and about ____ in diameter
5 feet long
2.5 INCHES in diameter
The large intestine begins at the _______ and ends at the ____
ileocecal valve
anus
The wall of the large intestine forms a series of _____ with creases called _____
pouches
tinae coli
1st part of Large intestine
Cecum
The Cecum receives material from the ____
ileum
The Cecum is considered a
Blind Pouch
The vermiform appendix looks like a ____ and is apart of the _____
Worm
Cecum
The 2nd part of the Large intestine
Ascending colon
The ascending colon is located on the ______
right side of the abdominal cavity
The ascending colon extends from the
Cecum to the hepatic flexure (where it turns)
The 3rd part of the colon is the
Transverse colon
The transverse colon extends from across the
abdomen from the hepatic flexure to the splenic flexure
The 4th part of the Large intestine is called the
Descending colon
The Descending colon is located at the
left side of the abdomen
The Descending colon extends from the
Splenic flexure to the sigmoid flexure
The 5th part of the Large intestine is the
Sigmoid colon
The sigmoid colon starts at the ____ and empties into the _____
sigmoid flexure
rectum
The sigmoid colon is __ shaped which bends ______
S shaped
bends posteriorly
The 6th part of the Large intestine is the
Rectum
The Rectum is the last _____ of the large intestine (size)
15 CM
The rectum stores
Fecal matter
The rectum contains the Anal canal and contains 2 sphincters which are the
Internal Anal Sphincter
and the External anal Sphincter
The internal anal sphincter is ________ while the external anal sphincter is _________
Involuntary
Voluntary
Normal flora in the Large intestine produce (3)
Vitamin K
Biotin
Vitamin B5
The Large intestine is responsible for the absorption of (2)
Water and Bile Salts
The Large intestine stores ____ and is responsible for
Stores waste
Responsible for Defecation
Defecation is the
elimination of Undigested waste
Where is the Pancreas located
Posterior to the stomach in the UPPER LEFT QUADRANT
Pancreas produces Sodium Bicarbonate which is a
Weak base that neutralizes acidic chyme that reaches the small intestine
Pancreatic Secretions that travel through the pancreatic duct join the __________ and empties into the ________
Common bile duct
Duodenum
The liver is the ______ (size)
largest gland
The liver is located in the
Right Upper Quadrant
The liver has ___ lobes __ and __
two lobes left and right
The liver receives blood from the __________ and _________ by the _______ vein
GI tract and spleen by the hepatic portal vein
What does the liver store (3)
Glycogen, Vitamins, Iron
The Liver synthesizes (3)
plasma proteins (albumin and clotting factors)
Urea
Bile
The liver destroys _____ and detoxifies ______
RBCs
Detoxifies harmful substances
The Liver modifies _____ to enhance ____
lipids
to enhance their use by cells
What is first pass effect
The first-pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism whereby the concentration of a drug is greatly reduced before it reaches the systemic circulation. It is the fraction of lost drug during the process of absorption which is generally related to the liver and gut wall. Notable drugs that experience a significant first-pass effect are imipramine, morphine, propranolol, buprenorphine, diazepam, midazolam, demerol, cimetidine, and lidocaine.
Bile is needed for the _____ and is the color ______
digestion of lipids
green secretion
Bile _____ fat. _____ means
Emulsifies
Emulsify means to break up into small droplets
The gallbladder is the ________ sac/pouch on the interior surface of the _____ that stores ______
Muscular
Liver
Bile
Bile travels via ______ into the ______
Cystic duct to the gallbladder
The gallbladder absorbs ______ from the concentrated bile
Water
What are enzymes
Enzymes are protein catalysts that speed up the reactions involved in digestion
Food goes in the mouth then into the _______ then into the _______
Pharynx
Esophagus
Food goes from the Esophagus then into _______ then into ________
Stomachs Cardiac Sphincter
Stomachs Pyloric Sphincter
Food goes from the Stomachs Pyloric Sphincter then into _______ then into _____
Duodenum
Jejunum
Food goes from the Jejunum then into ______ then into ______
Ilium
Cecum
Food goes from the Cecum then into the ______ then into the _______
Ascending colon
Transverse colon
Food goes from the Transverse colon then into the ______ then into the ________
Descending colon
Sigmoid
Food goes from the Sigmoid then into the __________ then into the _______
Rectum
Internal anal Sphincter
Food goes from the Internal anal sphincter then into the _______ then _______
External Anal Sphincter
Out the body
The 3 parts the mouth consists of are the
Tongue
Teeth
Saliva
The 2 parts that belong to the pharynx are called the
And the 2 parts that close passageways are the
Oropharynx and Laryngopharynx
Uvula and Epiglottis
The stomach is responsible for ________ digestion and ______ digestion
Chemical and Mechanical
The small intestine consists of (3)
Duodenum
Jejunum
Ilium
The large intestine consists of (6)
Cecum Ascending colon Transverse colon Descending colon Sigmoid Rectum
The anus consists of
Internal and External Sphincter
Amylase is produced by (2)
Salivary glands + Pancreas
Amylase is located in (2)
Mouth + Duodenum
Amylase acts on
Turning Starch or CHO –> Disaccharides
Pepsin is produced by
Chief cells in the stomach
Pepsin is located in
The stomach
Pepsin acts on
Protein –> Peptides
HCI is produced by
Parietal cells in the stomach
HCI is located in
The stomach
HCI acts on
Protein
Bile is produced by
The Liver
Bile is located in the
Duodenum
Bile acts on
Emulsifies fat
Lipase is produced by
The pancreas
Lipase is located in the
Duodenum
Lipase acts on
Lipids –> Fatty acids + glycerol
Trypsin / Chymotrypsin is produced by the
Pancreas
Trypsin / Chymotrypsin is located in the
Duodenum
Trypsin / Chymotrypsin acts on
Protein —> Peptides
Sucrase / Maltase / Lactase is produced by
Duodenum
Sucrase / Maltase / Lactase is Located in the
Duodenum
Sucrase / Maltase / Lactase acts on
Disaccharides –> Monosaccharides
Peptidases is produced by
Duodenum
Peptidases is located in the
Duodenum
Peptidases acts on
Peptidases –> amino acids
Carbohydrate starts in the mouth with the help of
Salivary Amylase
The end product of Starch (carbohydrate) digestion is
Monosaccharides
Protein Digestion starts in the ______ with ______ and _____
stomach
HCI and Pepsin
The end of protein digestion is
Amino Acids
Fat digestion starts in the
Small Intestines
The end product of fat digestion is (2)
Fatty acids and Glycerol
Parasympathetic Stimulation (Vagus Nerve) does …..
increases the production of digestive secretions and increases motility of the GI tract
Parasympathetic Stimulation occurs due to (2)
Sight and smell of food
Stomach distention
Peristalsis is the ______ of the G.I.
Motility
Sympathetic Stimulation leads to a ……
decrease in the production of digestive secretions and decreases motility of the GI tract
Gastrin is secreted by
G cells in the stomach
Gastrin is produced in response to
stomach distention, presence of caffeine in the stomach, or presence of partially digested protein in the stomach
What are the functions of gastrin
secretion of large amounts of gastric juice, and closure of the cardiac sphincter
When is Gastric Inhibitory Peptide secreted
When chyme enters the small intestine
What are the functions of GIP
inhibits the secretion of gastric juices and decreases gastric motility
Stimulates the release of insulin
When is Secretin secreted
When chyme enter the small intestine
What are the functions of Secretin
Decreases gastric secretions
What does Secretin Stimulates (3)
the release of water and bicarbonate from the pancreas
release of bile of liver
insulin
When Cholecystokinin CCk secreted
When fat enters small intestine
What does CCK stimulate
release of digestive enzymes from the pancreas
release of bile from the gallbladder
CCk inhibits ________ _________ and may feel pain in the ____
gastric emptying
RUQ
The Small intestine is responsible for the absorption of (3)
digested starch, proteins, and lipids
The Large intestine is responsible for the absorption of (2)
Water vitamins and minerals
What happens when there is a spinal reflex by the reflex initiated by the presence of fecal matter in the rectum
Defecation
Defecation can have several ______ ______ defects
Neural tube
The internal anal sphincter is
involuntary
The external anal sphincter is
voluntary
Both sphincters must ____ in order for defecation to occur
Relax
Name some effects of aging
decreased sense of appetite and taste
decreased peristalsis
decreased secretions in g.i.
decreased intrinsic factor
decreased muscle tone of cardiac sphincter
Decreased intrinsic factor can lead to
Pernicious anemia
Decreased Muscle tone can lead to
increase in pyrosis(Heartburn) / GERD
Describe intrinsic factor
a substance secreted by the stomach that enables the body to absorb vitamin B12. It is a glycoprotein
Plasma proteins and Clotting factors come from
Liver