Digestive System Flashcards
What is physical digestion?
Using teeth and muscle action to break down food into smaller pieces to increase its surface area for absorption
What is chemical digestion?
Breaking down large, insoluble molecules into smaller, soluble molecules using hydrolysis by enzymes
What are the 2 main functions of the digestive system?
- To break down food into nutrients needed for metabolic processes
- Remove waste products
What are the 5 main constituents/ nutrients of food?
- Carbohydrates
- Protein
- Fats
- Vitamins and Minerals
- Dairy
What are the 2 parts of the digestive system?
- Alimentary Canal (GI Tract)
2. Accessory Organs
What are the 6 parts of the alimentary canal?
- Mouth
- Pharynx
- Oesophagus
- Stomach
- Small Intestine
- Large Intestine
What are the 5 accessory organs?
- Teeth
- Salivary Glands
- Pancreas
- Liver
- Gall Bladder
What is another name for the mouth and what is it lined with?
Oral cavity, lined with a mucous membrane
What forms the lateral walls of the oral cavity?
Cheeks
What forms the anterior and posterior roof of the oral cavity?
Anterior = hard palate Posterior = soft palate
What is the uvula?
A fleshy finger-like projection of the soft palate which extends downwards
What is the vestibule?
The space between the lips and cheeks externally and the teeth and gums internally
Describe the tongue
Muscular and has several bony attachments such as the hyoid bone and styloid processes of the skull
What is the lingual frenulum?
A fold of mucous membrane which secures the tongue to the floor of the mouth
What is the name of the situation in which the lingual frenulum is very short?
Tongue-tie
What are the 3 types of salivary gland?
- Parotid gland
- Sublingual gland
- Submandibular gland
What are tonsils?
Collections of lymphatic tissue located at the posterior end of the oral cavity
What are the 4 main types of tonsils?
- Palatine
- Pharyngeal
- Lingual
- Tubal
What is tonsillitis?
An illness in which the pharyngeal tonsil becomes inflamed and swollen and obstructs the nasopharynx, forcing the person to breathe through their mouth and making swallowing difficult and painful
What are the 3 sections of the pharynx?
- Nasopharynx
- Oropharynx
- Laryngopharynx (continuous with the oesophagus)
Where is the oesophagus located?
Runs from the mouth to the stomach passing through the diaphragm
What are the 4 layers of the oesophagus wall?
- Mucosa (inner)
- Submucosa
- Muscularis Externa
- Serosa (outer)
What are the 2 nerve plexuses in the alimentary canal and what is their function?
- Submucosal nerve plexus
- Myenteric nerve plexus
To regulate mobility and secretory activity
Where is the stomach located?
On the left side of the abdominal cavity, hidden mostly by the liver and diaphragm
What is the small intestine and where is it located?
- The major digestive organ
- Muscular tube extending from the pyloric sphincter to the large intestine
- The longest section of the alimentary tube
What is the average length of the small intestine?
2.5 - 7m
What are the 3 subdivisions of the small intestine and what percentage do they account for?
- Duodenum (5%)
- Jejunum (<40%)
- Ileum (<60%)
What is significant about the walls of the small intestine?
They have microvilli in the absorptive cells that increase surface area and the plasma membrane bears enzymes that complete the digestion of proteins and carbohydrates
What 3 accessory organs are associated with the small intestine?
- Pancreas
- Liver
- Gall Bladder
What is the pancreas and what is its function?
- A triangular gland that extends across the abdomen to the spleen and duodenum
- Produces enzymes that break down digestible foods by secreting them into the duodenum
What is the liver and what is its function?
- Largest gland in the body
- Located under the diaphragm on the right side of the body
- Has 4 lobes
- Produces bile, a yellow-to-green watery fluid that leaves the liver via the common hepatic duct
What is the gall bladder and what is its function?
- Thin-walled, green organ
- Stores bile when food digestion is not occurring
What is mastication?
Chewing
Outline the 5 steps of ingestion
- Food is placed in mouth, triggering large amounts of saliva to be produced
- Tongue mixes the food and saliva
- Mastication occurs, breaking down food into smaller pieces
- A bolus is created ready for swallowing
- Salivary amylase begins chemical digestion of starch to maltose
What is propulsion and what are the 2 phases?
- Swallowing and peristalsis
- 1st phase = buccal phase = voluntary
- 2nd phase = pharyngeal-oesophageal phase = involuntary
What is the name for the process of swallowing?
Deglutition
Which parts of the digestive system must work together to achieve Deglutition?
- Tongue
- Soft palate
- Pharynx
- Oesophagus
Describe the process of Deglutition
- The tongue blocks off the mouth and the soft palate closes off the nasal passages
- The larynx rises and is covered by the epiglottis
- Food moves into the pharynx and then the oesophagus
What is Peristalsis?
Wave-like contractions of the muscular wall of the oesophagus to propel food along
Describe the process of Peristalsis
- First longitudinal muscles contract and then the circular muscles
- Food at the distal end of the oesophagus presses against the cardioesophageal sphincter, opening it
How long does food take to reach the stomach?
3-4 seconds
How long does liquid take to reach the stomach?
1-2 seconds
What liquid is produced in the stomach and what is it’s function?
- Gastric juices, secreted by glands in the stomach lining
- Contain protein-digesting enzymes, mucous and HCl
What is unique about the stomach lining?
It has a protective mucosal layer to protect the lining and the rest of the gut from HCl
What does HCl activate and what does this substance do?
Activates pepsinogen to pepsin, a protein-digesting enzyme
What do the pancreatic juices contain?
Secondary amylase to continue breaking down carbohydrates
Why is secondary amylase required?
Salivary amylase is denatured by stomach acid
Describe the process of digestion in the stomach
- 3 muscle layers compress and pummel the food to break it down to form Chyme
- Peristalsis moves food through the stomach to the pyloric valve, which only allows liquids and small particles through into the small intestine
- When the duodenum is filled with Chyme and the wall is stretched, the enterogastric reflex occurs
How long does food stay in the stomach for?
4 hours (or 6 hours for meals high in fat)
How much Chyme does the pylorus of the stomach hold?
30ml
Why is the stomach acidic?
To kill bacteria
What is the enterogastric reflex?
Stimulated by a pH of 3-4 (duodenum) or 1.5 (stomach), causing the stomach to stop releasing gastric acid which stops digestion
How long does the food spend in the small intestine?
3-6 hours
Which 2 liquids digest food in the small intestine?
Pancreatic juices and bile
How is food absorbed in the small intestine?
By the epithelial cells, which are renewed every 2-3 days
What are the 4 main enzymes in the small intestine and what do they break down?
- Pancreatic amylase (starch)
- Trypsin (secreted as trypsinogen and activated by Enterokinase - digests protein)
- Chymotrypsin and Carboxypeptidase (protein)
- Pancreatic Lipase (fat)
What are the 3 main disaccharides broken down into?
- Maltose –> Glucose + Glucose
- Sucrose –> Glucose + Fructose
- Lactose –> Glucose + Galactose
What are the 2 main functions of Secretin?
- Increases the output of pancreatic juice rich in bicarbonate and bile from the liver
- Inhibits gastric mobility and gastric gland secretion
What are the 3 main functions of Cholecystokinin?
- Increases output of pancreatic juice rich in enzymes
- Stimulates gall bladder to expel stored bile
- Relaxes sphincter of duodenal papilla to allow bile and pancreatic juice to enter the duodenum
What is the function of bile?
- Acts as a ‘detergent’ to emulsify large fat globules into small ones which increases surface area for the action of pancreatic lipase
- Aids absorption of fats and fat-soluble vitamins (A, D, E and K)
What is intrinsic factor and what is it needed for?
- A glycoprotein produced in the parietal cells of the stomach
- Aids absorption of vitamin B12
How are most digestive products absorbed?
By active transport into the capillary beds of the villi to be transported to the liver
How are lipids absorbed?
Passive diffusion into the villi and are transported to the liver by the blood and lymphatic fluids
What is left at the end of the ileum?
Water, indigestible food and bacteria
How long does food stay in the large intestine for?
12-24 hours
What is the function of bacteria in the large intestine?
Metabolise remaining nutrients, release gas and make vitamins B and K
What is absorbed in the large intestine?
Vitamins and water
What are the 2 types of contraction in the large intestine?
- Haustral Contraction - slow segmenting movements lasting 1 minute
- Mass Movement - long slow-moving powerful waves that force the food residue to the rectum
Describe the Defecation reflex
- Spinal reflex from the sacral region
- Causes the walls of the sigmoid (descending) colon to contract and the anal sphincters to relax
- Faeces is forced through the anal canal
- Voluntary control
What may cause involuntary defecation problems?
Damage/injury to the spinal cord
What are the 2 sub-groups of Carbohydrates?
- Sugar
2. Starch
Give 3 sources of sugar
- Fruit
- Sugar cane
- Milk
Give 3 sources of starch
- Grains
- Legumes
- Root vegetables
What are the 4 sub-groups of Lipids?
- Saturated fats
- Unsaturated fats
- Cholesterol
- Protein-rich sources (incomplete)
Give 2 sources of saturated fat
- Animal products (meat and dairy)
2. Coconut
Give 2 sources of unsaturated fat
- Seeds
2. Nuts
Give 2 sources of cholesterol
- Egg yolk
2. Meat
Give 2 sources of protein-rich sources
- Legumes
2. Nuts
What are the 4 main Vitamins?
A, C, D and E
Give 2 sources of vitamin A
- Liver
2. Carrots
Give 2 sources of vitamin C
- Strawberries
2. Kiwi
Give 2 sources of vitamin D
- Tuna
2. Orange juice
Give 2 sources of vitamin E
- Almonds
2. Spinach
What are the 5 main minerals?
- Iron
- Calcium
- Zinc
- Phosphorus
- Potassium
Give 2 sources of iron
- Liver
2. Meat
Give 2 sources of calcium
- Seeds
2. Cheese
Give 2 sources of zinc
- Spinach
2. Beef
Give 2 sources of phosphorus
- Meat
2. Fish
Give 2 sources of potassium
- Avocado
2. Potato
Give 5 problems caused by lack of a balanced diet
- Malnourishment
- Vitamin deficiency
- Obesity
- Fatigue
- Constipation (lack of fibre)
What is the daily recommended intake of fibre?
24g