digestive system Flashcards

1
Q

structures of the digestive system

A
  • oral cavity, teeth and tongue
  • pharynx
  • esophagus
  • stomach
  • small intestine
  • large intestine
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2
Q

Accessory glands

A
  • salivary glands
  • liver
  • gall bladder
  • pancreas
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3
Q

Role of the digestive system

A

breaks down ingested food for the use of the body

  • chemical breaking of bonds releases energy and helps maintain body temperature.
  • rebuilding of food molecules into those needed requires energy
  • excess = defacation
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4
Q

6 essential activities

A
  1. ingestion
  2. mechanical digestion
  3. propulsion
  4. chemical digestion
  5. absorption
  6. defacation
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5
Q

1st layer of GI tract

A

serosa layer (visceral peritoneum)

  • tough, dense
  • blood vessels that go into gut
  • to protect internal layer
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6
Q

2nd layer of GI tract

A

muscularis externa

  • muscular layer
  • circular and longitunal layers
  • when contrcats - anables nutrients to move through the gut
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7
Q

3rd layer of GI tract

A

submucosa

  • connective tissue and blood supply
  • anchoring for mucosa
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8
Q

4th layer of GI tract

A

the only layer that is specialised

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9
Q

mechanical digestion

A
  • through chewing and muscular action the food is broken down to smaller and smaller pieces.
  • food is now chyme
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10
Q

chemical digestion

A
  • the addition of enzymes to the food causes chemical bonds to be broken
  • proteins - amino acids
  • staches and large polysaccharide sugar - monosaccharides
  • large lipid molecules - smaller molecules
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11
Q

How does food move through the GI tract ?

A
  1. swallowing in the oesophagus
  2. churning in the stomach
  3. expulsion to the small intestine
  4. mass movement in the large colon
  5. defecation from the anus
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12
Q

the function of the GI tract?

A
  1. local factors - stimulus for digestive activities
    - coordinates responses to changes in the pH of the contents of the lumen, physical distortion in the tract or presence of chemicals.
  2. neural control mechanisms
    - short reflex = chemoreceptors or stretch receptors by myenteric plexus
    - long reflex - interneuron and motor neuron to CNS move materials from one area to another
  3. Hormonal control mechanisms
    - 18 different hormones
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13
Q

Salivary glands

A
  • Salivary amylase
    commences breakdown of starches - small intestine
  • Salivary lipase
    activated in the stomach to assist in lipid breakdown - small intestine
  • Detention
    Proteolytic enzymes that kill bacteria in food
  • Mucous
    Moistens food
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14
Q

Role of the hard palate

A

underlain with bone: hard surface to aid with mechanical digestion

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15
Q

Role of the soft palate

A
  • skeletal muscle

- rises to close off the nasopharynx when we swallow.

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16
Q

Role of the tongue

A
  • skeletal muscel and mucous membrane
  • helps from of oral cavity
  • extrinsic muscles - position of tongue
  • intrinsic muscles - shape of tongue
  • papillae - taste

Functions

  • grips + re-positions food
  • mix food with saliva and form bolus
  • form words
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17
Q

How is food swallowed? (pharynx)

A
  1. Buccal phase
  2. pharyngeal phase
  3. esophageal phase
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18
Q

Buccal phase

A

contraction of the tongue to push the bolus up against the soft palate and then posteriorly into the oropharynx by the tongue and palate

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19
Q

pharyngeal phase

A

bolus moves from the oropharynx to the esophagus (involuntary)

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20
Q

esophageal phase

A

moves through the esophagus to the stomach

21
Q

Function esophagus

A

Mucus is secreted and muscular contractions propel food into the stomach. No digestive enzymes are secreted and no absorption takes place.

22
Q

Function of the stomach

A
  • mixing chamber and storage for ingested food
  • rugae for allowed increased volume
  • ## pyloric sphincter regulates movement of chyme into small intestine
23
Q

mucous epithelial cells

A
  • protect lining from acid and pepsin

- to help the churning into chyme

24
Q

Histamine

A

stimulate pareital cells to produce acid

25
Q

Pareital cells

A
  • HCL
  • INtrinsic factor = binds to b12 for absorption
  • cheif cells = produces pepsinogen which becomes pepsin in the presence of HCL
  • G cells = release gastric hormones to blood in response to muscle strength receptors.
26
Q

How is digestion controlled in the stomach

A
  1. Cephalic phase
  2. gastric phase
  3. intestinal phase
27
Q

cephalic phase

A
  • initiated by the sight, smell, thought and taste of food
  • signals from the CNS
  • conditioned reflex
28
Q

gastric phase - chewing

A
  • 2/3 of gastric secretion
  • ingested food stimulates gastric activity by stretching the stomach and rating the pH of its contents; causes a cascade of events that leads to the release of hydrochloric acid = lowers the ph to break apart the food.
  • stimulated by each, histamine and gasterin
29
Q

Intestinal phase

A
  • stretching of teh duodenum enhances gastric function via the vagal nerve, as the chyme causes the secretion of gastrin
  • ## the acid and semi-digested fats in the duodenum trigger the enterogastric reflex
30
Q

Digestion

A

Mouth = amylase begins carbohydrate digestion
stomach = hydrochloric acid and pepsin breaks down large proteins
small intestine = pancreatic enzymes release to duodenum and small intestine breakdown of carbohydrates and proteins.

31
Q

roles of liver

A
  • metabolism of carbohydrates, lipids, proteins
  • process drugs and hormones
  • synthesize bile salts (to emulsify fats)
  • Storage (glycogen, vitamins, minerals)
32
Q

Liver structure

A
  • 4 lobes = right, left, quadrate and caudate

- each lobe forms many lobes (hepatocytes and sinusoids)

33
Q

reticuloendolethal cells

A

central cells

34
Q

gall bladder function

A
  1. liver secretes bile
  2. in the gallbladder bile becomes more concentrated
  3. CCK (hormone) triggers dilation + contraction of gall bladder + eject to the small intestine to break down lipid.
35
Q

Role of endocrine pancreatic secretions

A
  • Glandular epithelial cells = secret pancreatic juices (enzymes)
  • Pancreatic islets
    Hormones
    Glucagon - increase rate of glycogen to glucose conversion
    Insulin - glucose storage
    somatostatin (GHIH) slow digestion by inhibiting digestion and absorption
36
Q

Pancreatic juices

A
  • 1200-1500 ml
  • ph = 7.1-8.2
  • h20
    salt
    sodium bicarbonate
37
Q

Enzymes in the pancreas

A
  • amylase
  • ligase
  • trypsinogen - to form trypsin - former breaks down proteins to amino acids
  • nucleases - digest DNA in food
38
Q

structure of the small intestine

A

3 sections

  • duodenum
  • lejunem
  • lleum
39
Q

characteristics of structures

A
  • villi (contains blood vessels, nerves and lymphatic capillaries)
  • microvilli ( brush border enzymes - digestive enzymes - brush border of the villi)
    Intestinal juices (1-2 L per day).
  • Mucosa (Solitary lymphatic nodules)
  • Submucosa (duodenal - alkaline secretion to neutralise stomach acid
40
Q

What happens to food in the small intestine ?

A
  • Duodenal brush border enzymes ( for further breakdown of proteins)
  • Lipases
    Bile facilitates attachment of lipases to lipids
  • Pancreatic amylase (complexes starch digestion)
  • Enzymes (completion of the digestion of starches, protein + lipids.
  • Passage of digested nutrients from GI tract into blood or lymph.
41
Q

Where within the GI tract does most absorption of nutrients take place?

A

In small intestine

  • small molecules produced by digestion are absorbed
  • the villi create SA for absorption

LArge intestine

  • water, salts and vitamins
42
Q

structure of the large intestine

A
- colon
Ascending 
Transverse 
Descending 
Sigmoid 
  • Caecum
    attached appendix
  • Anal canal
43
Q

Histology of large intestine

A
- Mucosa 
Absorphortive cells absorb mainly water 
Goblet cells secrete mucus 
- Muscularis 
contraction created by external smooth muscle + internal circular smooth muscle
44
Q

Movement of large intestines

A
- gastroileal reflex 
intensifies after a meal 
occurs 3/4 days 
- Haustrak churning 
Distension and contraction of haustra 
Mass peristalsis (absorption along the large intestine)
45
Q

Role of the large intestine

A

production and storage of faeces

  • water absorption to produce semi-dried chyme
  • Absorption of the bacterially produced vitamins
46
Q

Role of bacteria in the large intestine?

A
  • ferment carbohydrates
  • break down proteins
  • produce some vitamins
47
Q

How is defaecation controlled?

A
  • empties the rectum
  • response to distension of rectal wall
  • external and sphincter voluntary relaxes
48
Q

short reflex in the anus

A

senses of peristaltic contractions that move faeces towards the anus

49
Q

long reflex in the anus

A

mass movements that push faeces towards the reaction from descending and sigmoid colon