digestion Flashcards

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1
Q

what is digestion?

A

the hydrolysis of large molecules into smaller molecules that can be absorbed across cell membranes

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2
Q

where does physical digestion occur?

A

mouth (teeth) and stomach (churning)

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3
Q

where does chemical digestion occur

A

mouth stomach and ileum

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4
Q

what is the pancreas’ role in digestion

A

makes digestive enzymes but doesnt do any digesting and squirts its enzymes into small intestine

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5
Q

what is food digested by

A

extracellular enzymes

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6
Q

what are extra cellular enzymes

A

enzymes produced by epithelial cells

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7
Q

what is ingestion

A

taking in food

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8
Q

what is egestion

A

passing of food as faeces

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9
Q

what is excretion

A

the removal of metabolic waste

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10
Q

how are carbohydrates digested into their products

A

by the hydrolysis of glycosidic bonds

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11
Q

how is starch broken down

A

broken down by amylase (either in mouth or pancreas) into maltose

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12
Q

how is maltose broken down

A

maltose is broken down by enzyme maltase which is membrane-bound in ileum into two glucose molecules

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13
Q

how is lactose broken down

A

broken down by lactase into glucose and galactose

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14
Q

how is sucrose broken down

A

by enzyme sucrase into glucose and fructose

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15
Q

what enzymes digest proteins

A

peptidases

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16
Q

how are proteins digested

A

by hydrolysis of peptide bonds

17
Q

what do endopeptidases do

A

break peptide bonds inside protein

18
Q

what do exopeptidases do

A

break peptide bonds at ends of protein to form a dipeptide and two amino acids

19
Q

what do dipeptidases do

A

break peptide bond in a dipeptide forming two amino acids

20
Q

what is co transport

A

Co-transport is the coupled movement of substances across a cell membrane via a carrier protein. It involves a combination of facilitated diffusion and active transport.

21
Q

how are glucose/amino acids absorbed

A

1) Na+ actively transported out of cell into blood therefore forming diffusion gradient between lumen and cell
2) Na+ and glucose/amino acid enter cell from lumen via a co transporter protein
3) glucose enters cell via facilitated diffusion

22
Q

what is bile

A

Bile salts made by the liver, emulsify lipids in order to increase the surface area of the lipids, for greater access to lipases

23
Q

what are micelles

A

the combination of fatty acids and monoglycerides to form a structure

24
Q

what is the first step in digesting lipids

A

large lipid droplets are emulsified by bile into small lipid droplets

25
Q

what is the second step in digesting lipids

A

small lipid droplets are hydrolysed by lipases which are made in the pancreas into fatty acids and monoglycerides

26
Q

how are lipids absorbed

A
  1. micelles move to cell surface membrane of epithelial cells and breakdown into monoglycerides and fatty acids
  2. monoglycerides and fatty acids move across cell surface membrane by simple diffusion
  3. via the endoplasmic reticulumn and golgi, triglycerides are reformed and made into specialised vesicles called chylomicrons
  4. chylomicrons releases triglycerides by exocytosis out of cell and into lymph
27
Q

why do monoglycerides and fatty acids move across cell surface membrane via simple diffusion

A

because they are lipid soluble substances

28
Q

why do lipids need to be emulsified

A

emulsification of lipid droplets greatly increases surface area for lipase enzymes to work on