Diffusion, body fluid comp, transport Flashcards

1
Q

What refers to the movement of water down a concentration gradient?

A

osmosis

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2
Q

What causes osmotic flow?

A

number of particles (and not particle size) on one side of a permeable membrane

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3
Q

Difference between osmolarity and osmolality?

A

osmolarity: Osm/L h2o
osmolality: Osm/kg h2o
osmolality will differ due to environmental conditions

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4
Q

What describes the ability of solutions to cause cells to swell or shrink via osmosis?

A

Tonicity

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5
Q

How do tonicity osmolarity differ?

A

tonicity describes the ability of a solution to make a cell swell or shrink and osmolarity the movement of water down a concentration gradient

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6
Q

_____ solutions cause cells to swell;

_____ solutions cause cells to shrink

A

hypotonic; hypertonic

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7
Q

how can cells recover from tonicity?

A

They retain or dump solutes in the cell to balance

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8
Q

What are the three main fluid compartments?

A

Intracellular fluid, extracellular fluid, plasma

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9
Q

how much ICF is in the body

A

28 L

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10
Q

How much ECF is in the body

A

10.5 L

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11
Q

How much plasma is in the body?

A

3.5 L

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12
Q

What is the importance of plasma?

A

Plasma is important because the heart depends on it to generate cardiac output. Small changes in plasma volume can potentially cause large changes in arterial pressure.

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13
Q

Why is the body pH kept within a narrow range?

A

H ion excess denatures proteins

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14
Q

What are the body’s 3 primary acid defense mechanisms?

A

Proteins, phosphate, bicarbonate

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15
Q

What is the main acid buffer system in cells (including RBCs)?

A

proteins

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16
Q

How does a change in plasma pH affect K+ balance?

A

Plasma pH, if altered, can cause H+ ions to enter the plasma, which would kick out K+ ions to balance it. These potassium ions are dangerous for the heart’s function

17
Q

What is the main buffer system in the extracellular fluid?

A

bicarbonate

18
Q

What is diffusion and how is it affected by concentration, barrier permeability, and surface area?

A

Diffusion always goes from high to low concentration.

Diffusion increases with increased surface area and permeability

19
Q

Contrast the differences between pores, channels, and carriers

A

Pores- always open
Channels- gated
Carriers- binding step
Carriers fastest at low concentrations, slowest at high concentrations

20
Q

diffusion of molecules across the cell membrane via carrier proteins, channel proteins, or ions (e.g., glucose and fructose transport into cells via GLUT transporters)

A

facilitated diffusion

21
Q

The movement of molecules against their concentration gradient across a selectively permeable membrane. Requires ATP as an energy source.

A

primary active transport

22
Q

The use of the electrochemical gradient (e.g., generated by primary active transport) of one type of molecule to move another type of molecule against its gradient. Does not directly require ATP. Includes symporters (e.g., the sodium-glucose symporter) and antiporters (e.g., the sodium–hydrogen antiporter).

A

secondary active transport

23
Q

Main buffer in ICF

A

phosphate

24
Q

main buffer in ECF

A

bicarbonate

25
Q

main buffer in proteins

A

cells/blood