Diffuse Parenchymal Lung Diseases Flashcards
1
Q
DPLD Pathophys
A
- Inflam and fibrosis of pulm interstitium
2
Q
DPLD Sx
A
- Dyspnea
- Cough
3
Q
DPLD Dx
A
- H&P
- CXR
- CT
4
Q
DPLD Tx
A
- Best supportive care: O2, resp rehab, steroids
5
Q
DPLD of known causes Etiology
A
- Drugs
- Connective tissue diseases
- Environmental exposure (birds, farming chemicals)
- Occupational exposures (coal, asbestosis)
6
Q
Pneumoconioses Epi
A
- Common
- Mining, agriculture
- “Black lung”
7
Q
Pneumoconioses Etiology
A
- Occupational lung disease caused by inhalation of particulate materials (usually minerals)
8
Q
Pneumoconioses Pathophys
A
- Inflam rxn in lungs leading to fibrosis and lung dysfx
9
Q
Pneumoconioses Sx
A
- Long latency period
- Dyspnea
- Cough
10
Q
Pneumoconioses Dx
A
- H&P: work hx, exposure hx, smoking, fam hx
- CXR (usually abnl)
- CT, PFT, bronchoscopy, biopsy
11
Q
Pneumoconioses Tx
A
- Lung transplant is only real option for severe
- Remove causative agent
- Supportive care: O2, bronchodilators, immunosuppressant
12
Q
Sarcoidosis Epi
A
- RF: young adults, AA
13
Q
Sarcoidosis Pathophys
A
- Idiopathic
- Multisystem disease–lungs are most frequent site
14
Q
Sarcoidosis Sx
A
- Dyspnea
- Cough
- Usually stable and self-limiting (non-harmful)
15
Q
Sarcoidosis Dx
A
- HRCT shows 1-5 mm lung nodules along bronchovascular bundles and subpleurally
- Need biopsy to r/o other diseases