Diffuse Parenchymal Lung Diseases Flashcards

1
Q

DPLD Pathophys

A
  • Inflam and fibrosis of pulm interstitium
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

DPLD Sx

A
  • Dyspnea

- Cough

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

DPLD Dx

A
  • H&P
  • CXR
  • CT
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

DPLD Tx

A
  • Best supportive care: O2, resp rehab, steroids
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

DPLD of known causes Etiology

A
  • Drugs
  • Connective tissue diseases
  • Environmental exposure (birds, farming chemicals)
  • Occupational exposures (coal, asbestosis)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Pneumoconioses Epi

A
  • Common
  • Mining, agriculture
  • “Black lung”
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Pneumoconioses Etiology

A
  • Occupational lung disease caused by inhalation of particulate materials (usually minerals)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Pneumoconioses Pathophys

A
  • Inflam rxn in lungs leading to fibrosis and lung dysfx
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Pneumoconioses Sx

A
  • Long latency period
  • Dyspnea
  • Cough
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Pneumoconioses Dx

A
  • H&P: work hx, exposure hx, smoking, fam hx
  • CXR (usually abnl)
  • CT, PFT, bronchoscopy, biopsy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Pneumoconioses Tx

A
  • Lung transplant is only real option for severe
  • Remove causative agent
  • Supportive care: O2, bronchodilators, immunosuppressant
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Sarcoidosis Epi

A
  • RF: young adults, AA
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Sarcoidosis Pathophys

A
  • Idiopathic

- Multisystem disease–lungs are most frequent site

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Sarcoidosis Sx

A
  • Dyspnea
  • Cough
  • Usually stable and self-limiting (non-harmful)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Sarcoidosis Dx

A
  • HRCT shows 1-5 mm lung nodules along bronchovascular bundles and subpleurally
  • Need biopsy to r/o other diseases
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Sarcoidosis Tx

A
  • Steroids
17
Q

LAM Epi

A
  • Rare

- Young women

18
Q

LAM Etiology

A
  • Idiopathic, diffuse, progressive

- Accelerated by preg and supplemental estrogen

19
Q

LAM Pathophys

A
  • Proliferation of interstitial smooth muscle leading to cyst formation
20
Q

LAM Sx

A
  • Dyspnea

- Pneumothorax

21
Q

LAM Dx

A
  • HRCT

- Biopsy

22
Q

LAM Tx

A
  • Lung transplant
23
Q

Idiopathic Pulm Fibrosis (IPF) Epi

A
  • Common, progressive, fatal

- RF: M, >50, smoking, env exposure to particulate materials, viral inf, fam hx

24
Q

Idiopathic Pulm Fibrosis (IPF) Pathophys

A
  • Small lung volume
25
Q

Idiopathic Pulm Fibrosis (IPF) Sx

A
  • Exertional dyspnea
  • Nonproductive cough
  • Sx for many months
  • PE: fine insp crackles (Velcro rales) at bases
26
Q

Idiopathic Pulm Fibrosis (IPF) Dx

A
  • HRCT: “honeycombing”
  • Appearance of unusual interstitial pneumonia
  • PFTs: restrictive pattern w/ low TLC, FEV1, DLCO
  • CXR: lower lung reticular opacities
  • Surg lung biopsy (gold standard)
27
Q

Idiopathic Pulm Fibrosis (IPF) Tx

A
  • Steroids and immunosuppressant
  • O2 if needed
  • Pulm rehab
  • Lung transplant is only proven benefit