Differential diagnosis Flashcards

1
Q

(blank)is defined as the reduction of the total circulating red cell mass below normal limits.

A

anemia

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2
Q

Anemia is diagnosed base on what?

A

hematocrit, hemoglobin

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3
Q

hemoglobin and mcv depend on what?

A

age, sex, ethnicity

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4
Q

Newborns have higher what?

A

mcv

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5
Q

Limit for differentiatin anemia from normal is set at (blank)

A

2 sd

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6
Q

Hb is higher in males cuz of what?

A

testosterone anddrogens

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7
Q

anemias are classified based on MCV,RDW, HB, and blank

A

reticulocyte count

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8
Q

what does hypochromic mean?

A

reduced hb based on color

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9
Q

what are microcytic hypochromic anemias caused by?

A

disorders of hb synthesis, i.e thalassemias or iron deficiency

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10
Q

marocytic anemias are often associated with abnormalities that impair (blank) of erythroid precursors in the bone marrows?

A

maturation (retic count important)

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11
Q

nomochromic and normocytic anemias may be associated with anemia in (blank) disease

A

chronic

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12
Q

If the degree of reticulocytosis is adequate to replace the loss of red blood cells, the anemia is termed “blank.”
If not able to compensate then it will blank

A

compensated.

worsen

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13
Q

anemias may be based on what three types of defects of the red blood cell?

A

intrinsic, environmental, extrinisic

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14
Q

Production disordres cause the production of RBCs to be either blank or blank

A

hypoplastic, or aplastic

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15
Q

What can create normocytic RBC but not enough of them>?

A

drugs, newly replaced bone marrow, and infections

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16
Q

How can you get microcytic or macrocytic cells?

A

iron deficiency, b12 deficiency, folate deficiency, Hb chain disorders

17
Q

What are the extrinsic ways you can have a destruction disorder?

A

RBC marked with antigen and spleen pulls it off making it shriveled OR rbc can travel through a messed up organ making it shriveled.

18
Q

What are the intrinisc ways RBC can be messed up?

A

abnormal membrane or H chains or enzyme disorder

19
Q

What are the steps in definitive diagnosis?

A

H & P, Lab tests, Define anemia i.e. blood loss, production or destruction,

20
Q

What are some tests that can determine anemia?

A

CBC, Iron levels, FOlate and B12 levels, coombs, hemoglobim, retic count, bilirubi and blood and urine tests.

21
Q

 Anemia may be either relative ….

A

(due to increased plasma volume with a normal red blood cell mass)

22
Q

Anemia may be absolute…

A

due to decreased red blood cell mass