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AIP > DIARRHOEA > Flashcards

DIARRHOEA Flashcards

1
Q

name 5 infectious causes of bloody diarrhoea

A
  1. shigella
  2. e coli 0157
  3. schistosomiasis
  4. campylobacter jejuni
  5. salmonella
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2
Q

Which is more likely to present with bloody stool: UC or CD?

A

UC

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3
Q

What is the imaging of choice to rule out toxic megacolon?

A

AXR

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4
Q

What is the imaging of choice in acute IBD?

A

Flexible sigmoidoscopy

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5
Q

What gram and shape is c diff?

A

Gram+ rod

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6
Q

What is the management of c difficile? What is the management in life threatening c difficile infection?

A
  1. first-line therapy is oral metronidazole for 10-14 days
  2. if severe or not responding to metronidazole then oral vancomycin may be used
  3. fidaxomicin may also be used for patients who are not responding , particularly those with multiple co-morbidities
  • For life-threatening infections a combination of oral vancomycin and intravenous metronidazole should be used
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7
Q

What is the most likely antibiotic to lead to c diff?

A

Cephalosporin

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8
Q

What is the mostsevere complication of c diff (can lead to toxic megacolon)?

A

Pseudomembranous colitis

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9
Q

Smoking decreases the risk of UC or CD?

A

UC

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10
Q

Which antibodies are associated with UC?

A

pANCA

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11
Q

Which antibodies are associated with CD?

A

asca

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12
Q

name the two derm signs of IBD

A
  1. pyoderma gangrenosum
  2. erythema nodosum
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13
Q

Which IBD presents with cobblestone morphology?

A

CD

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14
Q

What is the mainstay of management of acute Crohns? If the patient has had two or more flares in the past 12 months what other therapy should be given alongside the mainstay? What investigation needs to be done before prescribing one of these?

A

IV corticosteroids and supportive care

Azathioprine or mercaptopurine, TPMT activity

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15
Q

What two medications are used in the maintenance of remission?

A
  • Mercaptopurine
  • Azathioprine
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16
Q

Management of UC depends on site and severity. What is the first line management in each of these situations?

  1. proctitis
  2. left sided colitis
  3. pancolitis
  4. severe pancolitis
A
  1. topical aminosalicylate
  2. topical aminosalicylate
  3. oral and topical aminosalicylate
  4. IV steroids
17
Q

What is the maintenance therapy in UC?

A

Oral or topical 5-ASA

18
Q

What type of pathogen causes Giardia and what is the management?

A
  1. a protozoan
  2. metronidazole
19
Q

What is the most common and most potentially severe complication of chronic pancreatitis?

A

Chronic pseudocysts

AIP (19 decks)

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