CHEST PAIN Flashcards
What needs to be seen on an ECG to make a diagnosis of a STEMI suitable for thrombolysis?
- >2mm ST elevation in adjacent chest leads OR
- >1mm in adjacent limb leads OR
- new LBBB
How long should be left between serial troponins and what is considered a significant discrepancy in terms of %?
6 hours
20%
What score estimates mortality risk for UA/NSTEMI?
TIMI score
What is the GRACE score?
The GRACE Score is a prospectively studied scoring system to risk stratifiy patients with diagnosed ACS to estimate their in-hospital and 6-month to 3-year mortality.
Name the 6 key drugs in initial ACS management including dose and route
- aspirin 300mg PO
- clopidogrel 600mg
- oxygen 15L/min in hypoxic patients
- diamorphine 2.5-10mg IV PRN for pain relief
- Metoclopramide 10mg IV
- GTN spray
What is the ideal time from door to balloon?
What time is permitted?
- 90 minutes
- 12 hours
During PCI what additional drug is typically given?
additional anticoagulant e.g. heparin or fondaparinux
If PCI is not available within what period of time there should be thromobolysis with what medication?
- 2 hours
- tPa (streptokinase/alteplase)
What is the GRACE score used for?
To assess 6 month-3 year mortality risk following a diagnosis of ACS
What is the medical management of NSTEMI and UA?
Dual antiplatelet therapy with aspirin and clopidogrel
What is the change associated with Barrett’s oesophagus?
Stratified squamous to columnar
What is the definitive management of a tension pneumothorax?
Chest aspiration into 2nd ICS MCL
What is Virchow’s triad?
- Hypercoagulability
- Haemostasis
- Endothelial injury
What Well’s score is considered indicative of DVT or PE?
>2
What is the management for PE?
DOAC as bridging and actual therapy
You can place a vena cava filter in patients who continue to develop thrombi despite anticoagulation – but remember that implanting a filter without adequate anticoagulation will increase the risk of thrombus.
Thrombolysis may be used if the PE is deemed ‘Massive’ – 50mg alteplase – as long as no contraindications