Diarrhea Flashcards
The ______ intestine absorbs almost all nutrients
small
What facilitates breakdown of food particles into molecules
in the SI?
Bile
Pancreatic Enzyme
Acute Diarrhea is considered < _______ weeks
Chronic is > _______ weeks
Acute: < 3 weeks
Chronic: >3 weeks
Absorption of water depends on ________
solutes
If solutes are not absorbed, water remains in the lumen
and ______ diarrhea occurs
osmotic
If secretion of water into the lumen exceeds reabsorption,
_______ diarrhea results, and is caused by bacterial toxins
or other agents that open channels to allow water loss
secretory
Infection of the SI can cause
water and nutrients to not be absorbed, resulting in ______ diarrhea,
and
destruction of the SI leading to exudation of serum and blood can
result in _________ diarrhea.
Osmotic
Secretory
Inflammatory cytokines from inflammatory cells
induces _______ diarrhea
secretory
Inflammation can cause loss of epithelium, which is replaced
by immature cells which are less functional.
This can cause malabsorption leading to ______ diarrhea
osmotic
Increased motility leads to decreased absorption
leading to ______ diarrhea
osmotic
Which types of metabolic endocrine disorders can
cause diarrhea?
Hyperthyroid
Addison’s
Diabetes
Small Bowel vs. Large Bowel Diarrhea?
Weight loss possible
Small bowel
Small Bowel vs. Large Bowel Diarrhea?
Vomiting
Small
Small Bowel vs. Large Bowel Diarrhea?
Flatulence
small (with malabsorption)
Small Bowel vs. Large Bowel Diarrhea?
Marked increase in defecation frequency
LARGE bowel
Small Bowel vs. Large Bowel Diarrhea?
Increased fecal VOLUME
SMALL bowel
Small Bowel vs. Large Bowel Diarrhea?
Tenesmus
Large
Small Bowel vs. Large Bowel Diarrhea?
Mucous in feces
Large
Small Bowel vs. Large Bowel Diarrhea?
Hematochezia
Large
Small Bowel vs. Large Bowel Diarrhea?
Melena
SMALL
Small Bowel vs. Large Bowel Diarrhea?
Steatorrhea possible
SMALL
Small Bowel vs. Large Bowel Diarrhea?
Dyschezia
LARGE
Gray, greasy poop is indicative of
Pancreas or biliary issue
Orange or yellow feces is indicative of
Biliary or Liver issues
Green feces is indicative of
Gall bladder issues
Black and tarry feces is indicative of
Bleeding in upper GIT
T/F:
Uremia can cause melena
TRUE
T/F:
Liver disease can cause melena
TRUE
T/F:
Mastocytosis can cause melena
TRUE
How is acute diarrhea (<3weeks) treated?
Symptomatic Tx:
Diet
Psyllium
Metronidazole
How is chronic diarrhea (> 3weeks) treated
if systemically well?
Determine if it is small or large bowel and go from there
What diagnostics are used in determining cause of diarrhea?
Rectal exam
Big 4/QATS and Fecal
What diagnostics are used in cases
of diarrhea (acute or chronic) where the patient is
systemically UNWELL?
QATS, BP
CBC, Chem, UA, Fecal
Imaging, rads
Hypoalbuminemia is seen on CHEM
in which 3 primary GI diseases?
PLE
Neoplasia
Pythiosis
Decreased TT4 and Normal FT4 indicates
this
Sick euthyroid syndrome
Ova and parasites like coccidia can be seen
on this type of fecal analysis
simple saline float
Inflammatory or neoplastic cells,
campylobacter,
and clostridium can be seen on this method of fecal analysis
Stained smear slide/ rectal scrape
Ova, parasites, and Giardia
can be seen on this method of fecal analysis
Zinc centrifugation
What is included on a GI Panel?
B12
Folate
TLI
PLI
What does low B12 on a GI Panel indicate?
Malabsorption from
primary GI dz or EPI
What does low Folate on a GI Panel indicate?
Malabsorption
What does HIGH folate on a GI Panel indicate?
Dysbiosis
What does LOW TLI on a GI Panel indicate?
EPI (Exocrine Pancreatic Insufficiency)
What does HIGH PLI (pancreatic lipase) on a GI Panel indicate?
Concurrent pancreatitis
T/F:
B12 and Folate on a GI Panel can tell you the
type of GI disease present, or rule out GI disease
FALSE!!
Cannot do either of these things
Speckling seen on US indicates
Inflammatory dz
Striations seen on US indicates
Lymphangestasia
Starting at the top white layer in an ultrasound and alternating
to the bottom layer, what is the order of layers of the
intestinal wall?
Lumen
Mucosa (thickest black layer)
Submucosa
Muscularis (black)
Serosa
What would you expect to see on US of the intestines
in a cat with lymphoma?
Muscularis thickening
(should not be thicker than the mucosa layer)
For fecal occult blood testing, the patient
cannot eat ___ at least 48 hours before testing
meat
Fecal Alpha Proteinase Inhibitor increases with
GI ______ loss
protein
Fecal Alpha Proteinase Inhibitor testing
is useful for differentiating
________ from other causes of low albumin
PLE
This is a marker of inflammation in people with
Colitis and Chron’s Disease
pANCAs
What are the 2 choices for helicobacter triple tx?
Amoxicillin, Clariththromycin, Metronidazole
Amoxicillin, Bismuth Subsalicylate, Metronidazole
What Rx diet is used to tx diarrhea?
Hill’s W/d
_____ drugs can deplete Folic Acid/ B9
sulfa
This topical activity steroid is 15X more potent than prednisolone
and has less systemic side effects
Budesonide
Which immune modulatory drug used in the tx of diarrhea
reduces cell mediated immune responses (T-cell suppression)?
Atopica/Cyclosporine
Which immune modulatory drug used in the tx of diarrhea
Inhibits lymphocyte activation and proliferation?
Azathioprine
Which immune modulatory drug used in the tx of diarrhea
Cross links cells DNA to treat small cell lymphoma or
high grade IBD?
Chlorambucil
Which immune modulatory drug used in the tx of diarrhea
should NEVER BE USED IN CATS?
Azathioprine
This drug is used for large bowel diarrhea, and is cleaved into
active components in the colon. It also has antibacterial and
antiinflammatory actions
Sulfasalazine
What drug used in the treatment of diarrhea
is radiopaque and causes dark stools?
Bismuth Subsalicylate!!
These are living microorganisms used to impart health benefits
Probiotics
These are dietary carbohydrates used to stimulate growth and
metabolism of enteric protective bacteria
PRE-biotics
Lactobacilli and Bifidobacteria are
probiotics
Bran, psyllium, lactosucrose, and fructoligosaccharides
are
PRE-biotics
These two things are natural anticoagulants
Antithrombin
Protein C
The breakdown product of cross-linked fibrin
D-Dimers
Factor 7 and the EXtrinsic pathway are tested by this
coagulation test
PT
Factors 8, 9, 11, 12, and the intrinsic pathway
are tested by this
coagulation test
PTT