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28 GI drugs > Diarrhea > Flashcards

Diarrhea Flashcards

1
Q

Antidiarrheal drugs (3 groups)

A

Opioids
Locally acting drugs
5-HT3 antagonist

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2
Q

Opioids for diarrhea (2 drugs)

A

Diphenoxylate

Loperamide

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3
Q

Most efficacious antidiarrheal agents (1 group)

A

Opioids

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4
Q

Locally acting antidiarrheal drugs (3 drugs)

A

Psyllium hydrophilic mucilloid
Calcium polycarbophil
Bismuth subsalicylate

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5
Q

Bismuth subsalicylate - indications

A

Infectious diarrhea

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6
Q

5-HT3 receptor antagonist used for diarrhea

A

Alosetron

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7
Q

Alosetron - MOA in diarrhea

A

Inhibits motility by motility by blocking 5-HT3 receptors, which inhibits release of ACh from intrinsic myenteric neurons.

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8
Q

Alosetron - indications

A

IBS with diarrhea (alternative treatment)

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9
Q

Alosetron - adverse effect

A

Ischemic colitis

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28 GI drugs (5 decks)

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