diagnostics for renal Flashcards

1
Q

what are the 6 functions of the kidney

A
  • eliminate toxic substances
  • regulate body water and solute conc
  • regulate acid-base balance
  • excrete nitrogenous waste (urea and crew)
  • regulate electrolyte comp
  • endocrine (EPO, renin, metabolites of VitD)
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2
Q

what are the 6 functions of the kidney

A
  • eliminate toxic substances
  • regulate body water and solute conc
  • regulate acid-base balance
  • excrete nitrogenous waste (urea and crew)
  • regulate electrolyte comp
  • endocrine (EPO, renin, metabolites of VitD)
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3
Q

what is GFR

A

rate fluid moves from plasma to glomerular filtrate

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4
Q

how is GFR measured

A

the rate a substance is cleared from plasma - crea, inulin

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5
Q

what affects GFR

A

renal perfusion and renal plasma flow

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6
Q

define renal failure

A

decreased renal function due to decreasing no of functional nephrons

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7
Q

define azotaemia

A

increase in non-protein nitrogenous compounds - usually urea ± crea

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8
Q

define uraemia

A

clinical signs and biochem abnormalities ass w loss of functional nephrons

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9
Q

signs of uraemia

A

d+, v+, anorexia, ulcerative stomatitis, GI haemorrhage (bruxism in ruminants)

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10
Q

what is USG

A

measure of kidneys ability to conc urine

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11
Q

what range = isosthenuric

A

1.008-1.012

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12
Q

what range = hyposthenuric

A
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13
Q

what range = conc

A
cat = 1.035
dog = 1.030
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14
Q

what is haematuria

A

intact blood in urine

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15
Q

what causes haematuria

A

trauma, cystitis, renal bleeding, GT bleeding

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16
Q

what is haemoglobinuria

A

contents of RBC in urine

17
Q

causes of haemoglubinuria

A

haemolytic anaemia, decreased HCT

18
Q

what is myoglobinuria

A

muscle oxygen carrying protein in urine

19
Q

causes of myoglobinuria

A

severe muscle damage

20
Q

causes of bilirubin in urine

A

overspill into urine when levels increase in blood due to haemolytic anaemia, liver dz, gall bladder or bile duct obstruction (higher threshold in cats)

21
Q

what is GFR

A

rate fluid moves from plasma to glomerular filtrate

22
Q

how is GFR measured

A

the rate a substance is cleared from plasma - crea, inulin

23
Q

what affects GFR

A

renal perfusion and renal plasma flow

24
Q

define renal failure

A

decreased renal function due to decreasing no of functional nephrons

25
define azotaemia
increase in non-protein nitrogenous compounds - usually urea ± crea
26
define uraemia
clinical signs and biochem abnormalities ass w loss of functional nephrons
27
signs of uraemia
d+, v+, anorexia, ulcerative stomatitis, GI haemorrhage (bruxism in ruminants)
28
what is USG
measure of kidneys ability to conc urine
29
what range = isosthenuric
1.008-1.012
30
what range = hyposthenuric
31
what range = conc
``` cat = 1.035 dog = 1.030 ```
32
what is haematuria
intact blood in urine
33
what causes haematuria
trauma, cystitis, renal bleeding, GT bleeding
34
what is haemoglobinuria
contents of RBC in urine
35
causes of haemoglubinuria
haemolytic anaemia, decreased HCT
36
what is myoglobinuria
muscle oxygen carrying protein in urine
37
causes of myoglobinuria
severe muscle damage
38
causes of bilirubin in urine
overspill into urine when levels increase in blood due to haemolytic anaemia, liver dz, gall bladder or bile duct obstruction (higher threshold in cats)