diagnostics for renal Flashcards

1
Q

what are the 6 functions of the kidney

A
  • eliminate toxic substances
  • regulate body water and solute conc
  • regulate acid-base balance
  • excrete nitrogenous waste (urea and crew)
  • regulate electrolyte comp
  • endocrine (EPO, renin, metabolites of VitD)
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2
Q

what are the 6 functions of the kidney

A
  • eliminate toxic substances
  • regulate body water and solute conc
  • regulate acid-base balance
  • excrete nitrogenous waste (urea and crew)
  • regulate electrolyte comp
  • endocrine (EPO, renin, metabolites of VitD)
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3
Q

what is GFR

A

rate fluid moves from plasma to glomerular filtrate

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4
Q

how is GFR measured

A

the rate a substance is cleared from plasma - crea, inulin

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5
Q

what affects GFR

A

renal perfusion and renal plasma flow

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6
Q

define renal failure

A

decreased renal function due to decreasing no of functional nephrons

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7
Q

define azotaemia

A

increase in non-protein nitrogenous compounds - usually urea ± crea

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8
Q

define uraemia

A

clinical signs and biochem abnormalities ass w loss of functional nephrons

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9
Q

signs of uraemia

A

d+, v+, anorexia, ulcerative stomatitis, GI haemorrhage (bruxism in ruminants)

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10
Q

what is USG

A

measure of kidneys ability to conc urine

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11
Q

what range = isosthenuric

A

1.008-1.012

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12
Q

what range = hyposthenuric

A
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13
Q

what range = conc

A
cat = 1.035
dog = 1.030
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14
Q

what is haematuria

A

intact blood in urine

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15
Q

what causes haematuria

A

trauma, cystitis, renal bleeding, GT bleeding

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16
Q

what is haemoglobinuria

A

contents of RBC in urine

17
Q

causes of haemoglubinuria

A

haemolytic anaemia, decreased HCT

18
Q

what is myoglobinuria

A

muscle oxygen carrying protein in urine

19
Q

causes of myoglobinuria

A

severe muscle damage

20
Q

causes of bilirubin in urine

A

overspill into urine when levels increase in blood due to haemolytic anaemia, liver dz, gall bladder or bile duct obstruction (higher threshold in cats)

21
Q

what is GFR

A

rate fluid moves from plasma to glomerular filtrate

22
Q

how is GFR measured

A

the rate a substance is cleared from plasma - crea, inulin

23
Q

what affects GFR

A

renal perfusion and renal plasma flow

24
Q

define renal failure

A

decreased renal function due to decreasing no of functional nephrons

25
Q

define azotaemia

A

increase in non-protein nitrogenous compounds - usually urea ± crea

26
Q

define uraemia

A

clinical signs and biochem abnormalities ass w loss of functional nephrons

27
Q

signs of uraemia

A

d+, v+, anorexia, ulcerative stomatitis, GI haemorrhage (bruxism in ruminants)

28
Q

what is USG

A

measure of kidneys ability to conc urine

29
Q

what range = isosthenuric

A

1.008-1.012

30
Q

what range = hyposthenuric

A
31
Q

what range = conc

A
cat = 1.035
dog = 1.030
32
Q

what is haematuria

A

intact blood in urine

33
Q

what causes haematuria

A

trauma, cystitis, renal bleeding, GT bleeding

34
Q

what is haemoglobinuria

A

contents of RBC in urine

35
Q

causes of haemoglubinuria

A

haemolytic anaemia, decreased HCT

36
Q

what is myoglobinuria

A

muscle oxygen carrying protein in urine

37
Q

causes of myoglobinuria

A

severe muscle damage

38
Q

causes of bilirubin in urine

A

overspill into urine when levels increase in blood due to haemolytic anaemia, liver dz, gall bladder or bile duct obstruction (higher threshold in cats)