Diabetic Drugs (T Bank)

Question 1

7. Hypoglycemia can result from the action of either insulin or an oral hypoglycemic. Signs and symptoms of hypoglycemia include:

Answer 1

Dizziness, confusion, diaphoresis, and tachycardia

Question 2

Nonselective beta blockers and alcohol create serious drug interactions with insulin because they

Answer 2

Mask the signs and symptoms of altered glucose levels

Question 3

Optimal time of preprandial injection & peak for Lispro:

Answer 3

• Optimal time of preprandial injection is 15 minutes
• No pronounced peak.

Question 4

If switching a patient from NPH insulin to glargine, the provider should:

Answer 4

decrease initial dose of glargine by 20% to avoid hypoglycemia

Question 5

Metformin is a primary choice of drug to treat hyperglycemia in type 2 diabetes because it:

Answer 5

Decreases glycogenolysis by the liver

Question 6

Prior to prescribing metformin, the provider should:

Answer 6

Draw a serum creatinine to assess renal function

Question 7

The action of “gliptins” is different from other antidiabetic agents because they:

Answer 7

Act on the incretin system to indirectly increase insulin production

Question 8

Sitagliptin has been approved for:

Answer 8

• Monotherapy in once-daily doses
• Combination therapy with metformin

Question 9

MOA of GLP-1 agonists:

Answer 9

Directly bind to a receptor in the pancreatic beta cell

Question 10

Exenatide (sq) should be given:

Answer 10

60 minutes prior to the morning and evening meal

Question 11

Avoid concurrent administration of exenatide with which of the following drugs?

Answer 11

1. Digoxin
2. Warfarin
3. Lovastatin