Cardiac Glycoside

Question 1

Why is digoxin give for Afib

Answer 1

Digoxin slows AV nodal conduction, resulting in a slower ventricular rate. It does not convert the rhythm directly. Slowing HR yields greater diastolic filling time, permitting improved myocardial oxygenation. Cardiac muscle with an improved supply–demand ratio may then return to sinus rhythm

Question 2

Digoxin MOA for HF tx

Answer 2

Inhibits Na+/K+-ATPase, increasing intracellular calcium and enhancing cardiac contractility.

Question 3

When should a digoxin level be drawn?

Answer 3

levels should be drawn at least 6 hours after the last dose

Question 4

S/S of Digoxin toxicity

Answer 4

including nausea, vomiting, diarrhea, confusion, irregular pulse, yellow vision, and green halos around lights.