Diabetes Module 3 Flashcards
Macro vascular complications of type 2 diabetes:
Cardiovascular system, coronary artery disease, peripheral artery disease, cerebrovascular disease
Micro vascular complications of diabetes:
Eyes: retinopathy, macular edema
Nerves: nueropathy
Kidneys: nephropathy
One of the microvascular complications of diabetes, an umbrella term for various noninflammatory disorders of the retina including some that cause blindness
Retinopathy
Swelling of the macula the part of the Eye use for reading and seeing fine detail
Macular edema
One of the microvascular complications of diabetes involving the nervous system. develops over time and can cause nerve damage throughout the body. Symptoms can involve the sensory, motor and autonomic - or involuntary - nervous system
Neuropathy
Narrowing of the coronary arteries that is usually the result of atherosclerosis
Coronary artery disease
Damage or dysfunction of the arteries outside the heart resulting in reduced blood flow especially the narrowing of an artery supplying blood to the legs
Peripheral artery disease
A sudden loss of neurological function caused by loss of blood flow to an area of the brain
Cerebrovascular disease
Partial paralysis of the stomach so that food Empties much more slowly if at all. Usually caused by damage to the Vagus nerve; symptoms include early satiety nausea and vomiting
Gastroparesis
Nonvascular complications of diabetes include
Gastrointestinal, genitourinary, hearing loss, ocular, dermatologic, infection, periodontal disease
Why does excess glucose cause cell death
Because cells cannot regulate the glucose themselves so they release the production of chemicals that injure the cell and damage the microvascular tour of the eye, kidney and peripheral nerves
Most common micro vascular complication of diabetes, 10,000 cases of blindness per year
Diabetic retinopathy
This type of retinopathy is typically in the first decade or early in second decade of the disease and is characterized by microaneurysms and blot hemorrhages
Non-proliferative retinopathy
This type of retinopathy is characterized by neovascularization and can lead to hemorrhage , formation of fibrous tissue and retinal detachment
Proliferative retinopathy
True or false? Patients with diabetes are at a greater risk for glaucoma and cataracts.
True
What is neovascularization?
The formation of new blood vessel
What is a micro aneurysm?
A microscopic aneurysm or bold or ballooning in the wall of an artery
What is a blot hemorrhage?
A result of increased vascular permeability; appears around with blurred edges and hard exudates which are yellow and sharply defined
Damage to the kidney especially to the glomerulus where the blood is filtered is called:
Nephropathy
Occurs in 20-40% of patients with diabetes and is leading cause of end stage renal disease
Nephropathy
Progression of nephropathy:
Onset: increased GFR
5-10 years after onset: microalbuminuria and decreasing GFR
Progression is characterized by microalbuminuria and further decreasing GFR
What is microalbuminuria?
Albuminuria that is characterized by relatively low rate of albumin excretion in the urine.
What is globular filtration rate,
The rate at which blood passes through the glomeruli; it is often used to assess kidney function
What is macro albuminuria?
Albuminuria that is characterized by relatively high rate of albumin excretion in the urine