DIABETES MEDS (EXAM 2)

Question 1

LISPRO, ASPART, GLULISINE

Answer 1

ACTION: RAPID
ONSET: 15 MIN
PEAK: 1-2 HR
HALF LIFE: 80 MIN
DURATION: 3-5 HR
ADMIN: SUBC, 15MIN OF MEALTIME
COMPATIBLE: CAN GIVE WITH NPH, DRAW LISPRO FIRST, GIVE IMMED

Question 2

REGULAR (HUMULIN R, NOVOLIN R)

Answer 2

ACTION: SHORT
ONSET: 30-60 MIN
PEAK: 2.5 HR
DURATION: 6-10 HR
ADMIN: SUBC, 30-60MIN BEFORE MEAL, IV
COMPATIBLE: MIX W NPH, STERILE WATER, NS, DONT MIX WITH GLARGINE

Question 3

ISOPHANE (NPH)

Answer 3

ACTION: INTERMEDIATE
ONSET: 1-2H
PEAK: 4-8H
DURATION: 10-18 HR
ADMIN: SUBC, MIX (CLOUDY)
COMPATIBLE: MIX W ASPART, LISPRO, REG, DONT MIX W GLARGINE

Question 4

DETEMIR (LEVEMIR)

Answer 4

ACTION: LONG
ONSET: GRADUAL
PEAK: 6-8 H
DURATION: - 24H
ADMIN: SUBC, 1/DAY OR 2/DAY, SAME TIME
COMPATIBLE: DO NOT MIX WITH ANY OTHER

Question 5

GLARGINE (LANTUS)

Answer 5

ACTION: LONG
ONSET: 1-2H
PEAK: NONE
DURATION: 24 HR
ADMIN: SUBC: 1/DAY OR 2/DAY, SAME TIME
COMPATIBLE: DO NOT MIX

Question 6

ORAL HYPOGLYCEMICS

Biguanides - Glucophage (metformin)

Answer 6

Reduces insulin resistance, decreased sugar production in liver, take with meals

lower blood glucose (inhibits glucose production, decrease absorption of glucose, increase insulin sensitivity)

No alcohol - risk for lactic acidosis
Discontinue before imaging tests (contrast) - 48 hrs (risk for kidney damage and lactic acidosis)

D/N, FLATULENCE, INDIGESTION, ABDOMINAL PAIN